19777-06-1Relevant academic research and scientific papers
Co2(CO)8as a Solid CO (g) Source for the Amino Carbonylation of (Hetero)aryl Halides with Highly Deactivated (Hetero)arylamines
Cheruku, Srinivas,Sajith, Ayyiliath M.,Narayana, Yatheesh,Shetty, Poornima,Nagarakere, Sandhya C.,Sagar, Kunigal S,Manikyanally, Kumara N.,Rangappa, Kanchugarkoppal Subbegowda,Mantelingu, Kempegowda
, p. 5530 - 5537 (2021/05/07)
Carbonylation of (hetero)aryl iodides/bromides with highly deactivated 2-aminopyridines using Pd-Co(CO)4 bimetallic catalysis is accomplished. The use of Co2(CO)8 as a solid CO(g) source enhanced reaction rates observed when compared to CO(g), and excellent yields highlight the versatility of the developed protocol. A wide range of electronically and sterically demanding heterocyclic amines and (hetero)aryl iodides/bromides employed for this study resulted in excellent yields of amino carbonylated products. The developed methodology was further extended to synthesize Trypanosome brucie and luciferase inhibitors.
2-Aminobenzimidazole and -benzoxazole as N-nucleophile in palladium-catalysed aminocarbonylation
Bényei, Attila,Gergely, Máté,Kollár, László
supporting information, (2020/03/13)
Palladium-catalysed aminocarbonylation of aryl iodides in the presence of 2-aminobenzimidazole and 2-aminobenzoxazole as N-nucleophile was carried out. Single CO insertion took place, however, instead of the expected carboxamides (C(O)NH) the correspondin
Copper-mediated amidation of heterocyclic and aromatic C-H bonds
Wang, Qiu,Schreiber, Stuart L.
supporting information; experimental part, p. 5178 - 5180 (2010/01/06)
A copper-mediated aerobic coupling reaction enables direct amidation of heterocycles or aromatics having weakly acidic C-H bonds with a variety of nitrogen nucleophiles. These reactions provide efficient access to many biologically important skeletons, in
Heterocyclic Photorearrangements. Photochemical Behaviour of Some 3,5-Disubstituted 1,2,4-Oxadiazoles in Methanol at 254 nm
Buscemi, Silvestre,Cicero, Maria G.,Vivona, Nicolo,Caronna, Tullio
, p. 931 - 935 (2007/10/02)
Photochemical behaviour of some 3,5-disubstituted 1,2,4-oxadiazoles in methanol at 254 nm has been investigated.Ring photoisomerization to the 1,3,4-oxadiazole heterocycle or formation of open chain compounds involving the nucleophilic solvent was shown to depend on the nature and the position of the substituent.Photoinduced ring closure into the benzimidazole system, involving a 3-N-phenylamino side chain sequence and a photolytic intermediate of the oxadiazole heterocycle, is also reported.
Heterocyclic Photorearrangements. Photoinduced Rearrangements of 1,2,4,-Oxadiazoles Substituted by an XYZ Side Chain Sequence
Buscemi, Silvestre,Vivona, Nicolo
, p. 1551 - 1553 (2007/10/02)
Photoinduced rearrangements of 1,2,4-oxadiazoles substituted by an XYZ side chain sequence at position 3 of the ring have been recognized.Examples taken out from previous results have been emphasized and some other patterns dealing with a 3-phenoxy and 3-
