19790-62-6

Basic information

• Product Name: Butanal, 4-phenoxy-
• CAS NO: 19790-62-6
• Molecular Formula: C10H12O2
• Molecular Weight: 164.204
• Mol File: 19790-62-6.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: Butanal, 4-phenoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanal, 4-phenoxy-(19790-62-6)
• EPA Substance Registry System: Butanal, 4-phenoxy-(19790-62-6)

Safety Data

• Hazardous Substances Data: 19790-62-6(Hazardous Substances Data)

Usage

General Description

4-Phenoxybutanal is a chemical compound with the molecular formula C10H12O2. It is a pale yellow liquid with a floral odor and is commonly used as a fragrance ingredient in various consumer products. It is also used as an intermediate for the synthesis of other chemicals. 4-Phenoxybutanal has been found to have low acute oral toxicity in animal studies, and there is limited information available on its potential health effects in humans. However, it is important to handle this chemical with care and follow proper safety procedures when working with it.

Upstream product

• 2243-43-8 4-phenoxybutyronitrile 
• 50-00-0 formaldehyd 
• 87841-77-8 2-(2-Phenoxy-ethylazo)-prop-2-yl-hydroperoxide 
• 109-92-2 ethyl vinyl ether 
• 98-59-9 p-toluenesulfonyl chloride 
• 70659-92-6 (4-azidobutoxy)benzene 
• 7647-01-0 hydrogenchloride 
• 60-29-7 diethyl ether 
• 201230-82-2 carbon monoxide 
• 1746-13-0 allyl phenyl ether 
• 32117-82-1 N-methoxy-N-methyl-formamide 
• 63985-67-1 (3-phenoxypropyl)triphenylphosphonium bromide 
• 108-95-2 phenol 
• 32833-70-8 4-phenoxybut-2-yn-1-ol 

Downstream Products

• 358349-92-5 (4-phenoxybutyl)benzene 
• 2653-86-3 (pent-4-en-1-yloxy)benzene 
• 19790-68-2 4-phenoxy-butyraldehyde-semicarbazone 

Relevant articles and documents

Binuclear Pd(I)-Pd(I) Catalysis Assisted by Iodide Ligands for Selective Hydroformylation of Alkenes and Alkynes

Since its discovery in 1938, hydroformylation has been thoroughly investigated and broadly applied in industry (>107 metric ton yearly). However, the ability to precisely control its regioselectivity with well-established Rh- or Co-catalysts has thus far proven elusive, thereby limiting access to many synthetically valuable aldehydes. Pd-catalysts represent an appealing alternative, yet their use remains sparse due to undesired side-processes. Here, we report a highly selective and exceptionally active catalyst system that is driven by a novel activation strategy and features a unique Pd(I)-Pd(I) mechanism, involving an iodide-assisted binuclear step to release the product. This method enables β-selective hydroformylation of a large range of alkenes and alkynes, including sensitive starting materials. Its utility is demonstrated in the synthesis of antiobesity drug Rimonabant and anti-HIV agent PNU-32945. In a broader context, the new mechanistic understanding enables the development of other carbonylation reactions of high importance to chemical industry.

Tunable P-Chiral Bisdihydrobenzooxaphosphole Ligands for Enantioselective Hydroformylation

Air-stable and tunable chiral bisdihydrobenzooxaphosphole ligands (BIBOPs) were employed in rhodium-catalyzed asymmetric hydroformylation of various terminal olefins with excellent conversions (>99%), moderate-to-excellent enantioselectivities (up to 95:5 er), and branched to linear ratios (b:l) of up to 400.

ALDEHYDE-SELECTIVE WACKER-TYPE OXIDATION OF UNBIASED ALKENES

This disclosure is directed to methods of preparing organic aldehydes, each method comprising contacting a terminal olefin with an oxidizing mixture comprising: (a) a dichloro-palladium complex; (b) a copper complex; (c) a source of nitrite; under aerobic reaction conditions sufficient to convert at least a portion of the terminal olefin to an aldehyde.