19806-14-5

Basic information

• Product Name: 2-[4-[4-(carboxymethyl)phenyl]phenyl]acetic acid
• CAS NO: 19806-14-5
• Molecular Formula: C₁₆H₁₄O₄
• Molecular Weight: 270.285
• Mol File: 19806-14-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 506.8°Cat760mmHg
• Flash Point: 274.4°C
• Density: 1.289g/cm³
• CAS DataBase Reference: 2-[4-[4-(carboxymethyl)phenyl]phenyl]acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-[4-(carboxymethyl)phenyl]phenyl]acetic acid(19806-14-5)
• EPA Substance Registry System: 2-[4-[4-(carboxymethyl)phenyl]phenyl]acetic acid(19806-14-5)

Safety Data

• Hazardous Substances Data: 19806-14-5(Hazardous Substances Data)

Usage

General Description

2-[4-[4-(carboxymethyl)phenyl]phenyl]acetic acid is a compound with the molecular formula C17H16O4. It is a derivative of acetic acid and contains two phenyl rings with a carboxymethyl group attached to one of them. 2-[4-[4-(carboxymethyl)phenyl]phenyl]acetic acid is often used as a building block in the synthesis of pharmaceuticals and agrochemicals. Its carboxylic acid group makes it a useful intermediate for the production of various esters, amides, and other derivatives. Additionally, its aromatic rings provide opportunities for interactions with biological targets, making it a potential drug candidate. Overall, 2-[4-[4-(carboxymethyl)phenyl]phenyl]acetic acid is a versatile chemical with applications in both the pharmaceutical and agrochemical industries.

Upstream product

• 7255-83-6 4,4’-bis(cyanomethyl)-1,1’biphenyl 
• 57186-86-4 diethyl <1,1'-biphenyl>-4,4'-diacetate 
• 42094-63-3 4,4'-Bis-(2,2,2-trichloro-ethyl)-biphenyl 
• 92-52-4 biphenyl 
• 92-87-5 p,p'-diaminobiphenyl 
• 1667-10-3 4,4'-bis(chloromethyl)biphenyl 
• 201230-82-2 carbon monoxide 
• 92-86-4 4-(4-bromophenyl)bromobenzene 
• 25848-29-7 diethyl 4,4’-bis(phenylglyoxylate) 
• 105077-03-0 [4'-(Ethoxycarbonyl-methylsulfanyl-methyl)-biphenyl-4-yl]-methylsulfanyl-acetic acid ethyl ester 

Downstream Products

• 106064-89-5 5,5'-(4,4'-Biphenylylen)bis(2-phenyl-1,3-dithiolylium-4-olat) 
• 106064-78-2 DL-4,4'-Biphenylylenbis<<(thiobenzoyl)thio>essigsaeure> 
• 855256-71-2 2-[4'-(2-oxo-2-piperidin-1-yl-ethyl)-biphenyl-4-yl]-1-piperidin-1-yl-ethanone 

Relevant articles and documents

Hydrophilic microporous lanthanide-organic frameworks based on 4,4′-biphenyldiacetate: Synthesis, crystal structures and sorption properties

Fifteen microporous coordination polymers of symmetrical and flexible 4,4′-biphenyldiacetate (bpda2–) with lanthanide(III) cations (Ln3+) of formula {[Ln2(bpda)3(H2O)]?2H2O}n(Ln?=?La (1), Ce (2), Pr (3), Nd (4), Sm (5), Eu (6), Gd (7), Tb (8), Dy (9), Ho (10), Er (11), Tm (12), Yb (13), Lu (14), Y (15)), have been synthesized and characterized. Single crystal X-ray diffraction (for 1, 3 and 4) in combination with powder X-ray diffraction showed isostructural compounds with an infinite secondary building unit (SBU). In this SBU, two crystallographically independent lanthanide ions are connected by three carboxylate groups in chelating-bridging mode to zig-zag Ln-carboxylate chains. These chains are assembled by the biphenyl part of the ligand to a 3D network with water molecules in channels with rectangular cross-sections of ～1.6?×?3??2. Thermogravimetric analysis indicates complete removal of the water molecules at 150?°C and thermal stability up to 380?°C. Stability studies on compound 1 show no degeneration in crystallinity after refluxing in water or different organic solvents. The dehydrated compound 1 exhibited no N2or H2uptake at 77?K and no CH4or CO2uptake at 273?K up to 1?bar. High-pressure (17?bar, 273?K) CO2uptake of dehydrated [Ln2(bpda)3]ncorresponded to the formation of {[Ln2(bpda)3]·CO2}nwith about 40% of the adsorbed CO2retained upon desorption. Water vapor sorption of activated and hygroscopic [Ln2(bpda)3]nreformed {[Ln2(bpda)3(H2O)]·2H2O}n. 4,4′-Biphenyldiacetic acid (H2bpda) shows blue emission, its europium 6 and terbium 8 compounds show red and weak green luminescence under UV light irradiation, with the bpda2?ligand acting as an antenna ligand for the europium(III) ions.

Non-planar oligoarylene macrocycles from biphenyl

Saddle- and propeller-shaped macrocycles are obtained by fourfold Perkin condensations in transient high dilution of 4,4′-bis(phenylglyoxylic acid) with either 4,4′-bis(phenylacetic acid) or p-phenylenediacetic acid, followed by four-fold oxidative photoc

An efficiently cobalt-catalyzed carbonylative approach to phenylacetic acid derivatives

A highly efficient cobalt-catalyzed carbonylative approach to phenylacetic acid derivatives under one atmosphere pressure is reported. This methodology represents a useful extension of benzimidazole used as ligand in metal catalysis, and the catalytic mechanism has been proved by computer simulation. Notably, this new cobalt precatalyst, which promotes the carbonylation reaction dramatically and has already been used for scale-up experiment of phenylacetic acid derivatives.