7255-83-6

Usage

Uses

Used in Pharmaceutical Industry:
2-[4-[4-(cyanomethyl)phenyl]phenyl]acetonitrile is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to be incorporated into the molecular structures of potential therapeutic agents. Its reactivity allows for the creation of diverse drug candidates with different properties and applications.
Used in Dye and Pigment Industry:
In the dye and pigment industry, 2-[4-[4-(cyanomethyl)phenyl]phenyl]acetonitrile is utilized as a starting material for the production of various dyes and pigments. Its chemical versatility enables the development of a wide range of colorants with unique characteristics for use in different applications.
Used in Research and Development:
2-[4-[4-(cyanomethyl)phenyl]phenyl]acetonitrile is employed as a starting material in research and development for the synthesis of novel chemical entities. Its high reactivity makes it an ideal candidate for exploring new chemical reactions and creating compounds with potential therapeutic or industrial uses.
Used in Organic Synthesis:
As a building block in organic synthesis, 2-[4-[4-(cyanomethyl)phenyl]phenyl]acetonitrile is used to construct complex organic molecules. Its ability to participate in various chemical reactions allows chemists to create a broad spectrum of products with diverse properties, expanding the scope of chemical research and innovation.

Upstream product

• 1667-10-3 4,4'-bis(chloromethyl)biphenyl 
• 151-50-8 potassium cyanide 
• 92-52-4 biphenyl 
• 773837-37-9 sodium cyanide 
• 20248-86-6 4-4'-bis(bromomethyl)biphenyl 
• 143-33-9 sodium cyanide 

Downstream Products

• 19806-14-5 <1,1'-biphenyl>-4,4'-diacetic acid 
• 1227300-73-3 C₂₉H₁₈N₂ 
• 1227300-74-4 C₄₂H₂₄N₂ 
• 855256-71-2 2-[4'-(2-oxo-2-piperidin-1-yl-ethyl)-biphenyl-4-yl]-1-piperidin-1-yl-ethanone 

Relevant academic research and scientific papers

Hydrophilic microporous lanthanide-organic frameworks based on 4,4′-biphenyldiacetate: Synthesis, crystal structures and sorption properties

Fifteen microporous coordination polymers of symmetrical and flexible 4,4′-biphenyldiacetate (bpda2–) with lanthanide(III) cations (Ln3+) of formula {[Ln2(bpda)3(H2O)]?2H2O}n(Ln?=?La (1), Ce (2), Pr (3), Nd (4), Sm (5), Eu (6), Gd (7), Tb (8), Dy (9), Ho (10), Er (11), Tm (12), Yb (13), Lu (14), Y (15)), have been synthesized and characterized. Single crystal X-ray diffraction (for 1, 3 and 4) in combination with powder X-ray diffraction showed isostructural compounds with an infinite secondary building unit (SBU). In this SBU, two crystallographically independent lanthanide ions are connected by three carboxylate groups in chelating-bridging mode to zig-zag Ln-carboxylate chains. These chains are assembled by the biphenyl part of the ligand to a 3D network with water molecules in channels with rectangular cross-sections of ～1.6?×?3??2. Thermogravimetric analysis indicates complete removal of the water molecules at 150?°C and thermal stability up to 380?°C. Stability studies on compound 1 show no degeneration in crystallinity after refluxing in water or different organic solvents. The dehydrated compound 1 exhibited no N2or H2uptake at 77?K and no CH4or CO2uptake at 273?K up to 1?bar. High-pressure (17?bar, 273?K) CO2uptake of dehydrated [Ln2(bpda)3]ncorresponded to the formation of {[Ln2(bpda)3]·CO2}nwith about 40% of the adsorbed CO2retained upon desorption. Water vapor sorption of activated and hygroscopic [Ln2(bpda)3]nreformed {[Ln2(bpda)3(H2O)]·2H2O}n. 4,4′-Biphenyldiacetic acid (H2bpda) shows blue emission, its europium 6 and terbium 8 compounds show red and weak green luminescence under UV light irradiation, with the bpda2?ligand acting as an antenna ligand for the europium(III) ions.

Design and synthesis of two novel functional metal-organic microcapsules; An investigation into ligand expansion effects on the metal-organic microcapsules' properties

In this study, two novel metal-organic capsules were synthesized based on coordination-directed organization of two new extended tetrazolate ligands (1,4-bis((1H-tetrazol-5-yl)methyl)benzene (btmbenzene), 4,4′-bis((1H-tetrazol-5-yl)methyl)biphenyl (btmbiphenyl)) and Zn2+ ions. Furthermore, the function of these capsules in the inclusion of inorganic nanoparticles (Fe3O4), dyes (Rhodamine B) and drugs (5-fluorouracil) was investigated. Moreover, the effects of ligand expansion on the size, morphology, loading capacity and other properties of these capsules were studied. In addition, other morphologies of these coordination polymers were fabricated under different conditions. Finally, the obtained microcapsules were utilized for the synthesis of crystalline ZnO hollow spheres via a calcination method.

Cubic octanuclear Ni(II) clusters in highly porous polypyrazolyl-based materials

Two highly porous coordination polymers, containing rare octanuclear hydroxo-nickel clusters and long bis-pyrazolyl spacers, are shown to possess, after mild thermal treatment, lattice cavities up to 72% of the total crystal volume.

Synthesis and structure-activity relationships for biphenyl H3 receptor antagonists with moderate anti-cholinesterase activity

The combination of antagonism at histamine H3 receptors and inhibition of acetylcholinesterase has been recently proposed as an approach to devise putative new therapeutic agents for cognitive diseases. The 4,4′-biphenyl fragment has been repor

Dibasic non-imidazole histamine H3 receptor antagonists with a rigid biphenyl scaffold

A class of rigid, dibasic, non-imidazole H3 antagonists was developed, starting from a series of previously described flexible compounds. The original polymethylene chain between two tertiary amine groups was replaced by a rigid scaffold, compo