198135-69-2Relevant academic research and scientific papers
Palladium(0)-Catalyzed Dearomative [3 + 2] Cycloaddition of 3-Nitroindoles with Vinylcyclopropanes: An Entry to Stereodefined 2,3-Fused Cyclopentannulated Indoline Derivatives
Laugeois, Maxime,Ling, Johanne,Férard, Charlène,Michelet, Véronique,Ratovelomanana-Vidal, Virginie,Vitale, Maxime R.
, p. 2266 - 2269 (2017)
The palladium(0)-catalyzed diastereoselective dearomative cyclopentannulation of 3-nitroindoles with vinylcyclopropanes is described. This straightforward and highly atom-economical method leads to a wide range of functionalized indolines in good yields a
Convenient synthesis of masked aminoindoles by indium mediated one-pot reductive acylation of 3- and 2-nitroindoles
Roy, Sujata,Gribble, Gordon W.
, p. 51 - 56 (2007/10/03)
Unstable 3- and 2-aminoindoles arc generated in situ by indium mediated reduction of 3- and 2-nitroindoles and capped as the stable amides (or carbamate) in moderate to high yields under mild conditions in a one-pot procedure.
Synthesis and reactions of N-protected 3-nitroindoles
Pelkey,Gribble
, p. 1117 - 1122 (2007/10/03)
Treatment of N-protected indoles 3 with acetyl nitrate generated in situ at low temperatures affords the corresponding 3-nitroindoles 2 in good to excellent yields. Deprotection of 1-acetyl-3-nitroindole (2h) with DBU gives 3-nitroindole (1). Reaction of
One-step syntheses of the pyrrolo[3,4-b]indole and pyrrolo[2,3-b]indole ring systems from 3-nitroindoles
Pelkey, Erin T.,Gribble, Gordon W.
, p. 1873 - 1874 (2007/10/03)
The reaction of 1-ethoxycarbonyl-3-nitroindole with ethyl isocyanoacetate in the presence of DBU gives ethyl 4-ethoxycarbonyl-2,4-dihydropyrrolo[3,4-b]indole-3-carboxylate, averting a novel rearrangement that we previously reported with 3-nitro-1-phenylsu
