4770-03-0

Basic information

• Product Name: 3-Nitro-1H-indole
• Synonyms: 3-Nitro-1H-indole
• CAS NO: 4770-03-0
• Molecular Formula: C₈H₆N₂O₂
• Molecular Weight: 162.14544
• Mol File: 4770-03-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 362.6±15.0 °C(Predicted)
• Appearance: /
• Density: 1.425±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 13.96±0.30(Predicted)
• CAS DataBase Reference: 3-Nitro-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Nitro-1H-indole(4770-03-0)
• EPA Substance Registry System: 3-Nitro-1H-indole(4770-03-0)

Safety Data

• Hazardous Substances Data: 4770-03-0(Hazardous Substances Data)

Upstream product

• 487-89-8 Indole-3-carboxaldehyde 
• 703-80-0 3-acetylindole 
• 150-76-5 4-methoxy-phenol 
• 228412-76-8 3-nitro-1-(p-toluenesulfonyl)indole 
• 120-72-9 indole 
• 108-24-7 acetic anhydride 

Downstream Products

• 1431565-66-0 (S)-4-(2-(2-(3-(N-(tert-butoxycarbonyl)-methylsulfonamido)-1H-indol-1-yl)acetoxy)-2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)ethyl)-3,5-dichloropyridine 1-oxide 

Relevant articles and documents

Regioselective nitration of 3-acetylindole and its N-acyl and N-sulfonyl derivatives

3-Acetylindole reacts regioselectively with NO2BF4 in the presence of SnCl4 to produce 3-acetyl-5-nitroindole or 3-acetyl-6-nitroindole, depending on the temperature, both in excellent yields.

A mild and efficient method for the mononitration of aromatic compounds by cerium (III) ammonium nitrate in acetic anhydride

A mild and efficient method for the mononitration of aromatic and olefinic compounds is described. This method is especially useful for active substrates.