1982-65-6

Basic information

• Product Name: N-(4-methoxyphenyl)furan-2-carboxamide
• Synonyms: 2-furancarboxamide, N-(4-methoxyphenyl)-; N-(4-Methoxyphenyl)-2-furamide
• CAS NO: 1982-65-6
• Molecular Formula: C₁₂H₁₁NO₃
• Molecular Weight: 217.2206
• Mol File: 1982-65-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 263°C at 760 mmHg
• Flash Point: 112.9°C
• Density: 1.24g/cm³
• Vapor Pressure: 0.0106mmHg at 25°C
• Refractive Index: 1.598
• CAS DataBase Reference: N-(4-methoxyphenyl)furan-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methoxyphenyl)furan-2-carboxamide(1982-65-6)
• EPA Substance Registry System: N-(4-methoxyphenyl)furan-2-carboxamide(1982-65-6)

Safety Data

• Hazardous Substances Data: 1982-65-6(Hazardous Substances Data)

Upstream product

• 527-69-5 2-furancarbonyl chloride 
• 104-94-9 4-methoxy-aniline 
• 2948-14-3 furan-2-carboxylic acid phenyl ester 
• 609-38-1 furan-2-carboxylic acid amide 
• 696-62-8 para-iodoanisole 
• 15970-75-9 (4-Methoxyphenyl) 2-furyl ketoxime 
• 15970-74-8 furan-2-yl(4-methoxyphenyl)methanone 
• 88-14-2 2-furanoic acid 
• 64-17-5 ethanol 
• 1026046-13-8 2-furanoyl sulfonate 

Downstream Products

• 6436-31-3 N-(p-anisyl)furan-2-carboxyimidoyl chloride 
• 17572-12-2 furan-2-carbothioic acid p-anisidide 

Relevant articles and documents

Rapidly Activating Pd-Precatalyst for Suzuki-Miyaura and Buchwald-Hartwig Couplings of Aryl Esters

Esters are valuable electrophiles for cross-coupling due to their ubiquity and ease of synthesis. However, harsh conditions are traditionally required for the effective cross-coupling of ester substrates. Utilizing a recently discovered precatalyst, Pd-catalyzed Suzuki-Miyaura and Buchwald-Hartwig reactions involving cleavage of the C(acyl)-O bond of aryl esters that proceed under mild conditions are reported. The Pd(II) precatalyst is highly active because it is reduced to the Pd(0) active species more rapidly than previous precatalysts.

Determination of aromaticity indices of thiophene and furan by nuclear magnetic resonance spectroscopic analysis of their anilides

A series of m- and p-substituted anilides of benzoic acid, 2-thienoic acid, and 2-furoic acid were prepared and their 1H and 13C nmr spectroscopic characteristics were examined. In general, good correlations were observed between the chemical shifts of proton and carbon signals of the acyl aromatic rings and the Hammett σ. Plots of the chemical shift values of the carbonyl carbons of the benzanilides against those of the 2-thienamides and 2-furamides gave an excellent correlation and the values of the slopes are 0.79 and 0.52, respectively, in dimethyl sulfoxide-d6. The slopes could be considered as a set of aromaticity index.