15970-74-8

Basic information

• Product Name: 2-(4-METHOXYBENZOYL)FURAN
• Synonyms: 2-(4-METHOXYBENZOYL)FURAN;CHEMBRDG-BB 6597831;2-FURYL(4-METHOXYPHENYL)METHANONE;2-furyl(4-methoxyphenyl)methanone(SALTDATA: FREE)
• CAS NO: 15970-74-8
• Molecular Formula: C₁₂H₁₀O₃
• Molecular Weight: 202.21
• Mol File: 15970-74-8.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 336.9°C at 760 mmHg
• Flash Point: 157.5°C
• Appearance: /
• Density: 1.159g/cm³
• Vapor Pressure: 0.000109mmHg at 25°C
• Refractive Index: 1.543
• CAS DataBase Reference: 2-(4-METHOXYBENZOYL)FURAN(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-METHOXYBENZOYL)FURAN(15970-74-8)
• EPA Substance Registry System: 2-(4-METHOXYBENZOYL)FURAN(15970-74-8)

Safety Data

• Hazardous Substances Data: 15970-74-8(Hazardous Substances Data)

Usage

General Description

2-(4-Methoxybenzoyl)furan is a chemical compound with the molecular formula C13H10O4. It is a furan derivative that contains a benzoyl group and a methoxy group attached to the furan ring. 2-(4-METHOXYBENZOYL)FURAN is commonly used in the synthesis of various pharmaceuticals and agrochemicals, and it also exhibits potential biological activities, such as antioxidant and anti-inflammatory properties. 2-(4-Methoxybenzoyl)furan is also known for its role as a key intermediate in the production of other organic compounds. Overall, this chemical has a range of industrial and medicinal applications due to its unique structure and properties.

InChI:InChI=1/C12H10O3/c1-14-10-6-4-9(5-7-10)12(13)11-3-2-8-15-11/h2-8H,1H3

Upstream product

• 527-69-5 2-furancarbonyl chloride 
• 100-66-3 methoxybenzene 
• 4682-94-4 furan-2-yl(4-hydroxyphenyl)methanone 
• 77-78-1 dimethyl sulfate 
• 1226-42-2 1,2-bis(4-methoxyphenyl)-1,2-ethanedione 
• 110-00-9 furan 
• 100-07-2 4-methoxy-benzoyl chloride 
• 33397-21-6 tris(4-methoxyphenyl)bismuth 
• 108-95-2 phenol 
• 98-01-1 furfural 
• 5720-07-0 4-methoxyphenylboronic acid 
• 88-14-2 2-furanoic acid 
• 13331-23-2 fur-2-ylboronic acid 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 36726-85-9 2-(4-methoxyphenyl)pyridin-3-ol 
• 15970-75-9 (4-Methoxyphenyl) 2-furyl ketoxime 
• 100518-86-3 (furan-2-yl)-(4-methoxyphenyl)-methanol 
• 111609-58-6 1-(4-methoxyphenyl)-3,4-dihydropyrrolo[1,2-a]pyrazine 
• 136912-36-2 2-((4-methoxyphenyl)thiocarbonyl)furan 
• 860183-19-3 4-hydroxy-7-(4-methoxy-phenyl)-benzofuran-6-carboxylic acid 
• 1244620-40-3 N'-(furan-2-yl(4-methoxyphenyl)methylene)-4-methylbenzenesulfonohydrazide 
• 4682-94-4 furan-2-yl(4-hydroxyphenyl)methanone 

Relevant articles and documents

Novelmeta-benzothiazole and benzimidazole functionalised POCOP-Ni(ii) pincer complexes as efficient catalysts in the production of diarylketones

The synthesis of four novel non-symmetric Ni(ii)-POCOP pincer complexesmeta-functionalized with either benzothiazole or benzimidazole at the central aryl ring is described. All complexes were fully characterised in solution by various analytical techniques and the molecular structures in the solid state of complexes1b,2aand2bwere unequivocally determined by single crystal X-ray diffraction analysis. In addition, the Ni(ii)-POCOP pincer complexes were efficiently used as catalysts in the synthesis of diarylketones by cross-coupling reactions of functionalized benzaldehydes and boronic acid derivatives under relatively mild conditions. An important aspect of this transformation is the dependence on the steric properties of the donor groups (OPR2) of the pincer ligands, the more active compounds having the phosphinitos bearing isopropyl groups (1aand2a) than those containingtert-butyl substituents (1band2b).

Method Of Preparing Fused Ring Indeno Compounds

The present invention relates to methods of preparing fused ring indeno compounds that involves reacting together a dienophile and a lactone compound, in the presence of a catalyst, and a carboxylic acid anhydride. With some embodiments, the fused ring in

Synthesis and biological activities of new halophenols

A series of new halophenols were synthesized, and their structures were established on the basis of 1H, 13C NMR and mass spectral data. All of the prepared compounds were screened for their in vitro protein tyrosine kinase (PTK) and vascular smooth muscle cell (VSMC) proliferation inhibitory activity. Twelve halophenols showed significant PTK inhibitory activity, most of them exhibited stronger activities than that of genistein, a positive reference compound. Several halophenols also displayed moderate VSMC proliferation inhibitory activity, compound 8c showed higher activity than that of tetrandrine, a positive reference compound. The preliminary structure-activity relationships of these compounds were investigated and discussed. The results provided a foundation for the action mechanism study and further structure optimization of the halophenols.