198327-80-9Relevant academic research and scientific papers
On the synthesis of two dimethoxy-1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline regioisomers
Chackal, Sarah,Dudouit, Fabienne,Houssin, Raymond,Henichart, Jean-Pierre
, p. 615 - 622 (2007/10/03)
Many marine alkaloids are biologically active products and possess the 1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline core as a common feature. This is a report of the synthesis of two of the title molecules with confirmation of their structure.
Synthesis of 7,8-dimethoxy-2-oxo-1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline: A key intermediate en route to makaluvamines, discorhabdin C and other marine alkaloids of this group via vicarious nucleophilic substitution of hydrogen
Makosza, Mieczyslaw,Stalewski, Jacek,Maslennikova, Olga S.
, p. 1131 - 1133 (2007/10/03)
The title compound 1a, a key intermediate in synthesis of an important group of alkaloids, is efficiently prepared via vicarious nucleophilic substitution of hydrogen followed by simple transformations.
