198327-79-6Relevant academic research and scientific papers
Synthesis of 7,8-dimethoxy-2-oxo-1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline: A key intermediate en route to makaluvamines, discorhabdin C and other marine alkaloids of this group via vicarious nucleophilic substitution of hydrogen
Makosza, Mieczyslaw,Stalewski, Jacek,Maslennikova, Olga S.
, p. 1131 - 1133 (1997)
The title compound 1a, a key intermediate in synthesis of an important group of alkaloids, is efficiently prepared via vicarious nucleophilic substitution of hydrogen followed by simple transformations.
Synthesis of tripeptide mimetics based on dihydroquinolinone and benzoxazinone scaffolds
Dantas De Araujo, Aline,Christensen, Caspar,Buchardt, Jens,Kent, Stephen B. H.,Alewood, Paul F.
supporting information; experimental part, p. 13983 - 13986 (2012/01/06)
In the image: The design and synthesis of peptidomimetics that maintain the configuration of the triad Asp-Thr-Gly found in the catalytic site of the HIV-1 protease (see scheme) are described. By using regioselective nitration and reductive lactamisation,
On the synthesis of two dimethoxy-1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline regioisomers
Chackal, Sarah,Dudouit, Fabienne,Houssin, Raymond,Henichart, Jean-Pierre
, p. 615 - 622 (2007/10/03)
Many marine alkaloids are biologically active products and possess the 1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline core as a common feature. This is a report of the synthesis of two of the title molecules with confirmation of their structure.
