4097-63-6

Usage

InChI:InChI=1/C7H6N2O6/c1-15-6-3-4(8(11)12)2-5(7(6)10)9(13)14/h2-3,10H,1H3

Upstream product

• 623-11-0 1-methyl-4-nitrosobenzene 
• 351005-08-8 3-hydroxy-4-methoxy-2,6-dinitro-benzaldehyde 
• 3251-56-7 2-methoxy-4-nitrophenol 
• 613-70-7 2-methoxyphenyl acetate 
• 498-00-0 4-hydroxymethyl-2-methoxyphenol 
• 121-34-6 3-methoxy-4-hydroxybenzoic acid 
• 15969-08-1 6-methoxy-2-nitrophenol 
• 121-33-5 vanillin 
• 90-05-1 2-methoxy-phenol 
• 110-46-3 isopentyl nitrite 
• 486-29-3 lariciresinol 
• 19628-78-5 p-nitrosoguaiacol 
• 37987-22-7 4-hydroxy-5-methoxy-3-nitrobenzyl alcohol 
• 6635-20-7 isonitrovanillin 

Downstream Products

• 13661-34-2 1,2-dimethoxy-3,5-dinitrobenzene 
• 7659-29-2 3,5-dinitrocatechol 
• 754940-60-8 3.5-diamino-pyrocatechol-1-methyl ether 
• 41669-93-6 2-chloro-3,5-dinitro-anisole 
• 198327-79-6 (3-hydroxy-4-methoxy-2,6-dinitrophenyl)acetonitrile 
• 146495-41-2 (3,4-dimethoxy-2,6-dinitrophenyl)acetonitrile 
• 198327-80-9 3-Cyano-3-(3,4-dimethoxy-2,6-dinitro-phenyl)-propionic acid ethyl ester 
• 13077-75-3 2,3-dimethoxy-1,6-dihydroxybenzene 
• 100059-77-6 1-(2,6-dihydroxy-3,4-dimethoxy-phenyl)-2-methoxy-ethanone 
• 101252-48-6 2,4-diamino-1,6-dimethoxybenzene 
• 21268-85-9 2-amino-1-methoxy-3,5-dinitrobenzene 
• 1361519-50-7 tert-butyl (7-((2,6-dichlorobenzyl)oxy)-2-oxo-1,2,3,4-tetrahydroquinolin-5-yl)carbamate 
• 1361519-57-4 ethyl 2-(5-((tert-butoxycarbonyl)amino)-7-((2,6-dichlorobenzyl)oxy)-2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetate 
• 1361519-51-8 2-(5-((tert-butoxycarbonyl)amino)-7-((2,6-dichlorobenzyl)oxy)-2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetic acid 

Relevant academic research and scientific papers

Synthesis of tripeptide mimetics based on dihydroquinolinone and benzoxazinone scaffolds

In the image: The design and synthesis of peptidomimetics that maintain the configuration of the triad Asp-Thr-Gly found in the catalytic site of the HIV-1 protease (see scheme) are described. By using regioselective nitration and reductive lactamisation,

Nitration of aromatic compounds by Zn(NO3)2· 2N2O4 and its charcoal-supported system

Zn(NO3)2·N2O4 and its charcoal supported system were found to be efficient nitrating agents. Mononitration of aromatic compounds such as benzene, alkyl benzenes, halobenzenes, nitrobenzene, anisol, and the highly selective mono-, di-, and trinitration of phenol, and dinitraion of substituted phenols were also performed in the presence of these reagents.

On the synthesis of two dimethoxy-1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline regioisomers

Many marine alkaloids are biologically active products and possess the 1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline core as a common feature. This is a report of the synthesis of two of the title molecules with confirmation of their structure.

Nitration of electron-rich aromatic compounds by cerium ammonium nitrate coated on silica

Treatment of electron-rich aromatic derivatives with cerium (IV) ammonium nitrate coated on silica (CANSio2) affords nitro aromatic compounds. The scope and the limitation of this reaction are discussed.

Reaction of Ferulic Acid with Nitrite: Formation of 7-Hydroxy-6-methoxy-1,2(4H)-benzoxazin-4-one

Ferulic acid was reacted with nitrite under acidic conditions to give complex mixtures of products. Chromatographic purification afforded products that were characterized by 1H- and 13C-NMR spectral analyses. The major fluorescent product was identified as 7-hydroxy-6-methoxy-1,2(4H)-benzoxazin-4-one along with 3-methoxy-4-hydroxybenzaldehyde (vanillin) and 2-methoxy-4,6-dinitrophenol. The structure of the unusual benzoxazinone was confirmed by its chemical degradation in base to methyl-2,4-dihydroxy-5-methoxybenzoic acid.

Photoreactions of 2,4-Dinitro-6-(phenyliodonio)phenolate with Some Nucleophiles

2,4-Dinitro-6(phenyliodonio)phenolat (1) kann photochemisch mit Pyridin zu einem Pyridinium-Zwitterion 4, mit Phenylisocyanat zu einem 1,3-Benzoxathiol 5 und mit Thioharnstoffen zu λ3-Iodanen 6 umgesetzt werden.Ein denkbarer Mechanismus wird vo

Synthesis and Reactivity of 2-Oxidodiaryliodonium Zwitterions

The direct synthesis of three new 2-oxidoaryliodonium zwitterions from phenols and aryliodine(III) bistrifluoroacetate and their reaction with nucleophiles and electrophiles are reported.Especially noteworthy is the reactivity of 2-methoxy-3,5-dinitrophenyl(phenyl)iodonium tetrafluoroborate (15) which is hydrolysed by water and solvolysed by alcohols at room temperature.

KINETICS AND MECHANISM OF SUBSTITUTIVE NITRATION OF GUAIACOL DERIVATIVES WITH DILUTE NITRIC ACID

The kinetics of the nitration reactions of a series of compounds which model the guaiacylpropane unit of lignin (vanillin, vanillic acid, and vanillic alcohol) to dinitroguaiacol by dilute nitric acid and aqueous sulfuric-nitric acid mixtures were investigated.It was shown that the substitution of the functional groups at the para position to the hydroxyl by a nitro group does not include an intermediate nitrosation stage but takes place by a free-radical mechanism, involving the formation and dissociation of nitroquinolide compounds.

KINETICS AND MECHANISM OF THE NITRATION OF GUAIACOL WITH DILUTE NITRIC ACID

The kinetics of the nitration of guaiacol with dilute nitric acid to dinitroguaiacol were studied.It was established that the introduction of the first nitro group involves a nitrosation stage and subsequent free-radical oxidation of the obtained nitroso