1984-28-7

Usage

Uses

Used in Organic Synthesis:
4-Bromo-N-butylbenzenesulphonamide is used as a key intermediate in the synthesis of various organic compounds. Its unique structure allows for the creation of a wide range of derivatives, making it a valuable component in the development of new chemical entities.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 4-Bromo-N-butylbenzenesulphonamide is used as a starting material for the development of new drugs. Its chemical properties can be manipulated to create potential therapeutic agents, contributing to the advancement of medicinal chemistry.
Used in Chemical Research:
4-Bromo-N-butylbenzenesulphonamide is employed as a research compound in academic and industrial laboratories. It serves as a model compound for studying chemical reactions and understanding the behavior of similar molecules, furthering the knowledge in the field of chemistry.

InChI:InChI=1/C10H14BrNO2S/c1-2-3-8-12-15(13,14)10-6-4-9(11)5-7-10/h4-7,12H,2-3,8H2,1H3

Upstream product

• 109-73-9 N-butylamine 
• 142-96-1 dibutyl ether 
• 701-34-8 4-bromo-benzenesulfonic acid amide 
• 98-58-8 4-bromobenzenesulfonyl chloride 
• 90869-13-9 4-bromo-N-(but-3-en-1-yl)benzenesulfonamide 
• 6647-76-3 p-bromobenzenesulfonyl azide 

Relevant academic research and scientific papers

Biphenyl sulfonamide compound and method for preventing and controlling crop pests by using biphenyl sulfonamide compound

The invention provides a biphenyl sulfonamide compound or a pesticide pharmacologically acceptable salt thereof, and a method for preventing and treating crop pests by using the biphenyl sulfonamide compound. The biphenyl sulfonamide compound is a compound shown as a formula (I) in the specification. The method for preventing and controlling crop pests comprises the step of applying an effective amount of biphenyl sulfonamide compounds or pharmaceutically acceptable salts thereof to crops so as to control pests harmful to the crops. Surprisingly, the biphenyl sulfonamide compound provided by the invention has excellent prevention and treatment effects on pests, especially armyworms, cabbage caterpillars, small cutworms, beet armyworms, prodenia litura, plutella xylostella, spodoptera litura, corn borers, chilo suppressalis, southern rice borers and the like.

Experimental and Computational Studies on Cp*CyRh(III)/KOPiv-Catalyzed Intramolecular Dehydrogenative Cross-Couplings for Building Eight-Membered Sultam/Lactam Frameworks

Described herein is an unusual Cp*CyRh(III)-catalyzed intramolecular site-specific aryl C-H annulation, a highly chemoselective protocol providing direct access to eight-membered sultams/lactams with broad substrate/functional group tolerance. Experimental and computational studies reveal that such a transformation involves a unique PivOH-assisted aryl C-H activation/alkene insertion/β-H elimination/hydrogen-transfer process involving the Rh(III)-hydride species as the active intermediate with the concomitant release of H2 as the major byproduct, thus enabling the developed Cp*CyRh(III) catalysis with redox-neutral and highly atom-economical features.

Sulfonyl Azides as Precursors in Ligand-Free Palladium-Catalyzed Synthesis of Sulfonyl Carbamates and Sulfonyl Ureas and Synthesis of Sulfonamides

(Chemical Equation Presented). An efficient synthesis of sulfonyl carbamates and sulfonyl ureas from sulfonyl azides employing a palladium-catalyzed carbonylation protocol has been developed. Using a two-chamber system, sulfonyl azides, PdCl2, and CO gas, released ex situ from Mo(CO)6, were assembled to generate sulfonyl isocyanates in situ, and alcohols and aryl amines were exploited as nucleophiles to afford a broad range of sulfonyl carbamates and sulfonyl ureas. A protocol for the direct formation of substituted sulfonamides from sulfonyl azides and amines via nucleophilic substitution was also developed.

TiCl4-mediated direct N-alkylation of sulfonamides with inactive ethers

A TiCl4-mediated intermolecular or intramolecular direct N-alkylation reaction of sulfonamides with inactive ethers as alkylating agents was successfully achieved. This method provides a novel approach towards N-alkyl sulfonamides from inactive ethers via an easy workup procedure. Georg Thieme Verlag Stuttgart · New York.