198486-36-1Relevant academic research and scientific papers
Syntheses of myo-inositol-1,2,3,5- and 2,4,5,6-tetrakisphosphates, unusual inhibitors of myo-inositol-1,4,5-trisphosphae 3-kinase
Chung, Sung-Kee,Chang, Young-Tae
, p. 2715 - 2718 (1997)
D-myo-Inositol 1,4,5-trisphosphate [D-I(1,4,5)P3], a calcium mobilizing second messenger, is converted to D-I(1,3,4,5)P4 by D-I(1,4,5)P3-3-kinase. Efficient syntheses of I(1,2,3,5)P4 (2) and I(2,4,5,6)P4 (3), novel 3-kinase inhibitors, are reported.
