Bioorganic and Medicinal Chemistry Letters p. 2715 - 2718 (1997)
Update date:2022-07-29
Topics:
Chung, Sung-Kee
Chang, Young-Tae
D-myo-Inositol 1,4,5-trisphosphate [D-I(1,4,5)P3], a calcium mobilizing second messenger, is converted to D-I(1,3,4,5)P4 by D-I(1,4,5)P3-3-kinase. Efficient syntheses of I(1,2,3,5)P4 (2) and I(2,4,5,6)P4 (3), novel 3-kinase inhibitors, are reported.
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