198623-56-2

Basic information

• Product Name: 3,5-DIETHOXYBENZYL ALCOHOL
• Synonyms: 3,5-DIETHOXYBENZYL ALCOHOL;(3,5-diethoxyphenyl)Methanol
• CAS NO: 198623-56-2
• Molecular Formula: C₁₁H₁₆O₃
• Molecular Weight: 196.24
• Product Categories: Alcohols;C9 to C30;Oxygen Compounds
• Mol File: 198623-56-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 37-39 °C(lit.)
• Boiling Point: 326.6 °C at 760 mmHg
• Flash Point: >230 °F
• Appearance: /
• Density: 1.064 g/cm³
• Vapor Pressure: 8.65E-05mmHg at 25°C
• Refractive Index: 1.512
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3,5-DIETHOXYBENZYL ALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIETHOXYBENZYL ALCOHOL(198623-56-2)
• EPA Substance Registry System: 3,5-DIETHOXYBENZYL ALCOHOL(198623-56-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 198623-56-2(Hazardous Substances Data)

Usage

General Description

3,5-Diethoxybenzyl alcohol is a chemical compound that belongs to the category of benzyl alcohols. It is a white solid with a molecular formula C12H18O3 and a molecular weight of 210.27 g/mol. 3,5-Diethoxybenzyl alcohol is commonly used as a reagent in organic synthesis and pharmaceutical research due to its potential as a building block for various chemical reactions. Its properties make it a valuable intermediate in the production of pharmaceuticals, agrochemicals, and other fine chemicals. In addition, 3,5-Diethoxybenzyl alcohol is also used in the manufacturing of fragrances, dyes, and pigments. However, it is important to handle this compound with care, as it may cause irritation to the skin, eyes, and respiratory system, and should be stored and used in a well-ventilated area.

InChI:InChI=1/C11H16O3/c1-3-13-10-5-9(8-12)6-11(7-10)14-4-2/h5-7,12H,3-4,8H2,1-2H3

Upstream product

• 26153-38-8 3,5-dihydroxybenzaldehyde 
• 120355-79-5 3,5-diethoxybenzaldehyde 
• 64-67-5 diethyl sulfate 
• 29654-55-5 5-(hydroxymethyl)benzene-1,3-diol 
• 74-96-4 ethyl bromide 
• 2150-44-9 1-carbomethoxy-3,5-dihydroxybenzene 
• 198623-55-1 3,5-diethoxybenzoic acid methyl ester 

Downstream Products

• 1073142-73-0 3,5-diethoxybenzyl chloride 
• 238405-74-8 1-(bromomethyl)-3,5-diethoxybenzene 

Relevant articles and documents

Total synthesis of dysidavarone A

Dysidavarone A is a sesquiterpene isolated from the South China Sea sponge Dysidea avara and was reported that it showed significant anticancer activities. Because the compound has unique ‘dysidavarane’ carbon skeleton and potent biological activity, a se

Synthesis and potent antileukemic activities of 10-benzyl-9(10H)-acridinones

A novel series of 10-benzyl-9(10H)-acridinones and 1-benzyl-4-piperidones were synthesized and tested for their in vitro antitumor activities against CCRF-CEM cells. Assay-based antiproliferative activity study using CCRF-CEM cell lines revealed that the acridone group and the substitution pattern on the benzene unit had significant effect on cytotoxicity of this series of compounds, among which 10-(3,5-dimethoxy)benzyl-9(10H)-acridinone (3b) was found to be the most active compound with IC50 at about 0.7 μM. Compound 3b was also found to have antiproliferative activity against two other human leukemic cell lines K562 and HL60 using the MTT assay. The antitumor effect of 3b is believed to be due to the induction of apoptosis, which is further confirmed by PI (Propidium iodide) staining and Annexin V-FITC/PI staining assay using flow cytometry analysis.