238405-74-8

Upstream product

• 29654-55-5 5-(hydroxymethyl)benzene-1,3-diol 
• 198623-56-2 3,5-diethoxybenzyl alcohol 

Downstream Products

• 529496-34-2 2-[7-(3,5-diethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1λ⁶-benzo[f][1,2,5]thiadiazepin-2-yl]-propionic acid methyl ester 
• 1054620-34-6 2-[7-(3,5-diethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1λ⁶-benzo[f][1,2,5]thiadiazepin-2-yl]-pentanedioic acid 1-tert-butyl ester 5-methyl ester 
• 198623-57-3 diethyl 5-(cyanomethyl)benzene-1,3-dioate 

Relevant academic research and scientific papers

Total synthesis of dysidavarone A

Dysidavarone A is a sesquiterpene isolated from the South China Sea sponge Dysidea avara and was reported that it showed significant anticancer activities. Because the compound has unique ‘dysidavarane’ carbon skeleton and potent biological activity, a se

MACROCYCLIC TERTIARY AMINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

The present invention is directed to macrocyclic tertiary amine compounds represented by general formula (I), which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.