1993-09-5

Basic information

• Product Name: 3-FLUORO-PHENYLAMINE HCL
• Synonyms: 3-Fluoro-phenylamine hydrochloride;3-Fluro-phenylamine;3-FLUORO-PHENYLAMINE HCL ;3-fluoroaniline:hydrochloride;Benzenamine, 3-fluoro-, hydrochloride (1:1)
• CAS NO: 1993-09-5
• Molecular Formula: C₆H₆FN*ClH
• Molecular Weight: 147.5778832
• Mol File: 1993-09-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 186.3 °C at 760 mmHg
• Flash Point: 77.2 °C
• Appearance: /
• Vapor Pressure: 0.667mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-FLUORO-PHENYLAMINE HCL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-FLUORO-PHENYLAMINE HCL(1993-09-5)
• EPA Substance Registry System: 3-FLUORO-PHENYLAMINE HCL(1993-09-5)

Safety Data

• Hazardous Substances Data: 1993-09-5(Hazardous Substances Data)

Usage

Description

3-FLUORO-PHENYLAMINE HCL is a chemical compound that features a fluorine-substituted phenylamine molecule combined with hydrochloric acid. 3-FLUORO-PHENYLAMINE HCL is recognized for its unique properties due to the presence of the fluorine atom, which makes it a valuable building block in the synthesis of pharmaceuticals and agrochemicals. Its role in the development and production of various drugs has established it as a significant component in research and industrial applications.

Uses

Used in Pharmaceutical Industry:
3-FLUORO-PHENYLAMINE HCL is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to enhance the properties of the final drug products. The fluorine atom's electronegativity and small size can improve the drug's potency, selectivity, and metabolic stability.
Used in Agrochemical Industry:
In the agrochemical sector, 3-FLUORO-PHENYLAMINE HCL is utilized as a precursor in the production of pesticides and other agrochemicals. Its unique chemical characteristics contribute to the effectiveness and selectivity of these products in agricultural applications.
Used in Research and Development:
3-FLUORO-PHENYLAMINE HCL is employed as a research compound for exploring new chemical reactions and developing novel drug candidates. Its reactivity and the influence of the fluorine atom make it a versatile tool in medicinal chemistry and chemical biology research.
Used in Industrial Chemical Production:
3-FLUORO-PHENYLAMINE HCL is also used in industrial settings for the large-scale production of specialty chemicals and materials that leverage the benefits of fluorination in phenylamine structures, such as increased reactivity or altered physical properties.

InChI:InChI=1/C6H6FN.ClH/c7-5-2-1-3-6(8)4-5;/h1-4H,8H2;1H

Upstream product

• 372-19-0 meta-fluoroaniline 
• 99-33-2 3,5-dinitrobenoyl chloride 

Downstream Products

• 129158-02-7 3-(3-Fluoro-phenyl)-2,5-dimethyl-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one 
• 65783-23-5 N-tert-Butyl-N'-(3-fluoro-phenyl)-guanidine 
• 65783-27-9 N-(3-Fluorphenyl)-N'-phenylguanidin 
• 1428-10-0 N-(3-fluorophenyl)formamide 
• 20893-73-6 3-fluorophenyldiazonium chloride 
• 1070894-63-1 8-(4-fluorophenyl)-4-(cyclohexylamino)-1-(3-fluorophenyl)-1,3,8-triazaspiro[4.5]dec-3-en-2-one 
• 885115-45-7 tert-butyl 4-(cyclohexylamino)-1-(3-fluorophenyl)-2-oxo-1,3,8-triazaspiro[4.5]dec-3-ene-8-carboxylate 
• 1011732-06-1 tert-butyl 1-(3-fluorophenyl)-2-oxo-4-{[(trimethylsilyl)methyl]amino}-1,3,8-triazaspiro[4.5]dec-3-ene-8-carboxylate 
• 65783-19-9 N-(3-fluorophenyl)guanidine 
• 1789-04-4 2-methyl-3-(3-fluorophenyl)-quinazolin-4-one 
• 129157-96-6 6-Benzyl-3-(3-fluoro-phenyl)-2,5-dimethyl-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one 
• 120045-94-5 2-amino-6-(3-fluoroanilino)purine 

Relevant articles and documents

SPIROPIPERIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

The present invention is directed to spiropiperidine compounds of formula (I) and tautomers thereof, which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as