20893-73-6Relevant articles and documents
Halobenzene cyanopyrazole compound containing purine structure as well as preparation method and application
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Paragraph 0065, (2016/10/31)
The invention discloses a halobenzene cyanopyrazole compound containing a purine structure as well as a preparation method and an application. The halobenzene cyanopyrazole compound is a compound with a general structure (I) as shown in the specification or a pharmaceutically acceptable salt thereof. The compound is low in dosage, good in insecticidal efficacy, simple in technique, low in cost and wide in market prospect.
Parallel synthesis of "Click" chalcones as antitubulin agents
Utsintong, Maleeruk,Massarotti, Alberto,Caldarelli, Antonio,Theeramunkong, Sewan
, p. 510 - 516 (2013/07/28)
It has been shown that some chalcones are able to inhibit tubulin polymerization, giving cytotoxicity and destruction of tumoral vasculature. A library of 180 novel chalcone analogs has been synthesized via click chemistry and screened for their cytotoxic