1789-04-4

Basic information

• Product Name: 3-(3-Fluorophenyl)-2-methylquinazolin-4(3H)-one
• Synonyms: 3-(3-Fluorophenyl)-2-methylquinazolin-4(3H)-one;CHI-71
• CAS NO: 1789-04-4
• Molecular Formula: C₁₅H₁₁FN₂O
• Molecular Weight: 254.259
• Mol File: 1789-04-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 409.1°Cat760mmHg
• Flash Point: 201.2°C
• Appearance: /
• Density: 1.25g/cm³
• Vapor Pressure: 6.68E-07mmHg at 25°C
• Refractive Index: 1.621
• CAS DataBase Reference: 3-(3-Fluorophenyl)-2-methylquinazolin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-Fluorophenyl)-2-methylquinazolin-4(3H)-one(1789-04-4)
• EPA Substance Registry System: 3-(3-Fluorophenyl)-2-methylquinazolin-4(3H)-one(1789-04-4)

Safety Data

• Hazardous Substances Data: 1789-04-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H11FN2O/c1-10-17-14-8-3-2-7-13(14)15(19)18(10)12-6-4-5-11(16)9-12/h2-9H,1H3

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Relevant articles and documents

Palladium-catalyzed four-component carbonylative synthesis of 2,3-disubstituted quinazolin-4(3H)-ones: Convenient methaqualone preparation

A palladium-catalyzed four-component carbonylative cyclization reaction for the synthesis of 2,3-disubstituted quinazolin-4(3H)-ones has been developed. A range of different 2,3-disubstituted quinazolin-4(3H)-one derivatives were prepared in moderate to good yields employing simple and readily accessible 2-iodoanilines, nitro compounds and acid anhydrides as the synthetic precursors. Mo(CO)6 acted both as a solid CO source and a reductant. Notably, methaqualone as a sedative and hypnotic medication can be prepared easily in 68% yield (4b) under our conditions as well.

Phosphorus Pentoxide in Organic Synthesis. XXX. New Synthesis of 4(3H)-Quinazolinones

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