199585-08-5

Basic information

• Product Name: 2-fluorophenyl isopropylcarbamate
• Synonyms: 2-fluorophenyl isopropylcarbamate
• CAS NO: 199585-08-5
• Molecular Weight: 197.209
• Mol File: 199585-08-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-fluorophenyl isopropylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-fluorophenyl isopropylcarbamate(199585-08-5)
• EPA Substance Registry System: 2-fluorophenyl isopropylcarbamate(199585-08-5)

Safety Data

• Hazardous Substances Data: 199585-08-5(Hazardous Substances Data)

Upstream product

• 367-12-4 2-fluorophenol 
• 1795-48-8 Isopropyl isocyanate 

Downstream Products

• 28177-50-6 2-fluoro-6-iodophenol 
• 2040-89-3 2-bromo-6-fluorophenol 
• 2040-90-6 2-chloro-6-fluorophenol 
• 394-50-3 3-fluorosalicylaldehyde 
• 899427-26-0 2-fluoro-6-(hydroxydiphenylmethyl)phenyl isopropylcarbamate 
• 899427-18-0 2-fluoro-6-(trimethylsilyl)phenyl isopropylcarbamate 
• 899427-21-5 2-fluoro-6-iodophenyl isopropylcarbamate 
• 899427-22-6 2-bromo-6-fluorophenyl isopropylcarbamate 
• 899427-23-7 2-chloro-6-fluorophenyl isopropylcarbamate 

Relevant articles and documents

Synthesis of halogenated phenols by directed ortho-lithiation and ipso-iododesilylation reactions of O-aryl N-isopropylcarbamates

The regioselective synthesis of halogenated phenols via directed ortho-lithiation reactions of in situ N-silylated O-aryl N-isopropylcarbamates is reported. This protocol is complemented by ipso-iododesilylation reactions of C-silylated carbamates and iodine-magnesium exchange reactions, which are facilitated by the adjacent carbamoyl group. These methods provide an entry into a series of o-fluoro-, o-iodo-, and o,o′-diiodophenols in high yields which are otherwise difficult to obtain. Georg Thieme Verlag Stuttgart.