199998-75-9

Upstream product

• 93711-81-0 (4-nitrophenyl)methyl (4R,5R,6S)-3-[(diphenoxyphosphinyl)oxy]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate 
• 127768-03-0 (2S,4S)-2-allyloxycarbonylmethyloxymethyl-4-mercapto-1-(4-nitrobenzyloxycarbonyl)pyrrolidine 
• 4457-32-3 4-nitrobenzyl chloroformate 
• 127767-92-4 (2S,4R)-2-Allyloxycarbonylmethoxymethyl-4-methanesulfonyloxy-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester 
• 117811-74-2 (2S,4R)-2-Carboxymethoxymethyl-4-methanesulfonyloxy-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester 
• 127767-97-9 (2S,4S)-4-acetylthio-2-(allyloxycarbonylmethyloxymethyl)-1-(4-nitrobenzyloxycarbonyl)pyrrolidine 
• 117811-69-5 (2S,4R)-4-t-butyldimethylsilyloxy-2-methoxycarbonyl-1-(4-nitrobenzyloxycarbonyl)pyrrolidine 
• 117811-73-1 (2S,4R)-2-Carboxymethoxymethyl-4-hydroxy-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester 
• 104795-10-0 (2S,4R)-4-tert-butyldimethylsiloxy-2-hydroxymethyl-N-(4-nitrobenzyloxycarbonyl) pyrrolidine 
• 101803-29-6 (2S,4R)-4-hydroxy-2-methoxycarbonyl-1-(4-nitrobenzyloxycarbonyl)pyrrolidine 
• 117811-70-8 (2S,4R)-4-t-butyldimethylsilyloxy-1-chloroacetyl-2-(hydroxymethyl)pyrrolidine 
• 117811-71-9 (6S,8R)-8-t-butyldimethylsilyloxy-2-oxo-1-aza-4-oxabicyclo[4.3.0]nonane 
• 117850-20-1 (2S,4R)-2-carboxymethyloxymethyl-4-hydroxypyrrolidine 
• 117811-66-2 (2S,4R)-4-t-butyldimethylsilyloxy-2-hydroxymethylpyrrolidine 

Relevant academic research and scientific papers

Synthesis and antibacterial activity of novel 4-pyrrolidinylthio carbapenems - I. 2-alkoxymethyl derivatives

The synthesis and in vitro antibacterial activity of a novel series of 2-alkoxymethyl-4-pyrrolidinylthio-1β-methyl carbapenems are described. As a result of these studies, we discovered that FR27743 (19j) containing a novel 2-fluoroethoxymethyl substituen