200341-70-4

Upstream product

• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 132969-60-9 (2S)-3-[(4-methoxybenzyl)oxy]-2-methylpropanal 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 132969-71-2 methyl (2S)-[(4-methoxybenzyl)oxy]-2-methylpropanoate 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 136320-64-4 (2R)-3-[(4-methoxybenzyl)oxy]-2-methylpropanol 
• 143236-59-3 2-[(S)-3-(4-Methoxy-benzyloxy)-2-methyl-propoxy]-tetrahydro-pyran 

Downstream Products

• 1344072-67-8 C₂₀H₃₄O₃Si 
• 1344072-82-7 C₂₃H₃₄O₆ 
• 1344072-92-9 C₂₀H₃₀O₆ 
• 1344072-80-5 C₂₀H₂₈O₆ 
• 1344072-77-0 C₂₇H₄₆O₇Si 
• 1037197-61-7 (+)-tert-butyl(((2S,3S,4S)-6,6-dibromo-1-((4-methoxybenzyl)-oxy)-2,4-dimethylhex-5-en-3-yl)oxy)dimethylsilane 
• 200341-81-7 1-[(2S,3S,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-2,4-dimethyl-6-triethylsilanyl-hex-5-ynyloxymethyl]-4-methoxy-benzene 
• 200341-76-0 2,2-Dimethyl-propionic acid (2S,3R,4S)-3-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-2,4-dimethyl-pentyl ester 
• 200341-80-6 (+)-tert-butyl(((2S,3S,4S)-6,6-dibromo-1-((4-methoxybenzyl)-oxy)-2,4-dimethylhex-5-en-3-yl)oxy)dimethylsilane 
• 200341-74-8 2,2-Dimethyl-propionic acid (2S,3R,4S)-3-hydroxy-5-(4-methoxy-benzyloxy)-2,4-dimethyl-pentyl ester 
• 200341-78-2 (2S,3S,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-2,4-dimethyl-pentan-1-ol 
• 200575-34-4 (2S,3S,4S)-5-(p-methoxybenzyloxy)-2,4-dimethylpentane-1,3-diol 
• 856190-96-0 C₆₃H₁₀₉NO₁₅Si₂ 
• 856190-98-2 C₆₃H₁₀₇NO₁₄Si₂ 

Relevant academic research and scientific papers

A kiyooka aldol approach for the synthesis of the C(14)-C(23) segment of the diastereomeric analog of tedanolide C

The challenging synthesis of a quaternary center within the highly oxygenated setting of tedanolide C can be performed via a Kiyooka aldol reaction. Here, the diastereomeric analog of tedanolide C with the configurations between C10 and C20 opposite compared to the proposed structure was chosen as the synthetic target. The tetra-substituted silyl ketene acetal provides the southern hemisphere of tedanolide C in useful selectivities, and the absolute configuration of the newly generated quaternary center was determined by NOE experiments of the corresponding acetonide.

Total synthesis of antascomicin B

(Chemical Equation Presented) The structurally enticing antascomicin B (1), which exhibits potent immunosuppressant-antagonizing properties, has a complex polyketide structure. Key steps in its enantioselective total synthesis include a transannular catec

Synthesis of the C8-C15 segment of (+)-discodermolide

Succeeding to the preceding paper, stereoselective synthesis of the C8-C15 segment of (+)-discodermolide (1), the marine natural product having the potent immunosuppressive activity, is described in which the contiguous asymmetric ce