200341-74-8

Upstream product

• 3282-30-2 pivaloyl chloride 
• 200575-34-4 (2S,3S,4S)-5-(p-methoxybenzyloxy)-2,4-dimethylpentane-1,3-diol 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 200341-70-4 (2E,4R)-5-(4-methoxybenzyloxy)-4-methylpentan-2-enoate ethyl ester 
• 200341-72-6 (2E,4R)-5-(4-methoxybenzyloxy)-4-methyl-2-penten-1-ol 
• 136320-64-4 (2R)-3-[(4-methoxybenzyl)oxy]-2-methylpropanol 
• 132969-71-2 methyl (2S)-[(4-methoxybenzyl)oxy]-2-methylpropanoate 
• 132969-60-9 (2S)-3-[(4-methoxybenzyl)oxy]-2-methylpropanal 

Downstream Products

• 200341-76-0 2,2-Dimethyl-propionic acid (2S,3R,4S)-3-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-2,4-dimethyl-pentyl ester 
• 1037197-61-7 (+)-tert-butyl(((2S,3S,4S)-6,6-dibromo-1-((4-methoxybenzyl)-oxy)-2,4-dimethylhex-5-en-3-yl)oxy)dimethylsilane 
• 200341-81-7 1-[(2S,3S,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-2,4-dimethyl-6-triethylsilanyl-hex-5-ynyloxymethyl]-4-methoxy-benzene 
• 200341-80-6 (+)-tert-butyl(((2S,3S,4S)-6,6-dibromo-1-((4-methoxybenzyl)-oxy)-2,4-dimethylhex-5-en-3-yl)oxy)dimethylsilane 
• 200341-78-2 (2S,3S,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-2,4-dimethyl-pentan-1-ol 

Relevant academic research and scientific papers

Synthesis of the C8-C15 segment of (+)-discodermolide

Succeeding to the preceding paper, stereoselective synthesis of the C8-C15 segment of (+)-discodermolide (1), the marine natural product having the potent immunosuppressive activity, is described in which the contiguous asymmetric ce