200616-38-2

Usage

Uses

Used in Pharmaceutical Industry:
Fmoc-glu(osu)-otbu is used as an anti-influenza reagent, playing a crucial role in the development of treatments and preventive measures against influenza infections. Its chemical structure allows it to interact with specific targets in the influenza virus, thereby inhibiting its replication and spread.
Used in Chemical Synthesis:
In the chemical industry, Fmoc-glu(osu)-otbu serves as an important building block for the synthesis of various complex molecules, including peptides, pharmaceuticals, and other bioactive compounds. Its unique functional groups enable it to participate in a range of chemical reactions, making it a versatile component in the synthesis of novel molecules with potential applications in various fields.
Used in Research and Development:
Fmoc-glu(osu)-otbu is also utilized in research and development settings, where it can be employed to study the structure-activity relationships of various biologically active molecules. Its unique properties make it a valuable tool for understanding the mechanisms of action of different compounds and for designing new molecules with improved efficacy and selectivity.

Upstream product

• 82911-69-1 N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide 
• 45120-30-7 L-glutamic acid α-tert-butyl ester 
• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 84793-07-7 Fmoc-Glu-OtBu 

Downstream Products

• 1071429-55-4 N2-N,N-dimethylaminomethylene-10-formyl-Pte-Glu(NH(Boc-His(τ-Bu-4-yl)OMe))-OtBu 
• 1046806-32-9 (S)-4-(4-(4-((S)-2-amino-2-carboxyethyl)-1H-imidazol-1-yl)butylcarbonylamino)-2-(4-((2-amino-4-oxo-3,4-dihydropteridin-6-yl)methylamino)benzamido)-4-oxobutanoic acid 

Relevant academic research and scientific papers

Synthesis of artificial glycoconjugates of arginine-vasopressin and their antidiuretic activities

Arginine-vasopressin (AVP) derivatives modified at the glutamine side chain amide with carbohydrate via an alkylene spacer (1a-d) were synthesized from new glycosylated glutamine derivatives (3a-d) by solid-phase synthesis. Glycoconjugates of AVP modified

USES OF ANTI-CD3 ANTIBODY FOLATE BIOCONJUGATES

Described herein are anti-CD3 antibody folate bioconjugates and uses thereof in the treatment of diseases, conditions, and cancers.

Preparation method of N-fluorenylmethoxycarbonyl-gamma-(S-triphenylmethyl-cysteamine)-L-glutamic acid

The invention provides a preparation method of N-fluorenylmethoxycarbonyl-gamma-(S-triphenylmethyl-cysteamine)-L-glutamic acid. The preparation method mainly solves the technical problems of complexity, long period, high cost, and low yield of an original process, and comprises the following steps: (1) preparing N-fluorenylmethoxycarbonyl-L-glutamic acid; (2) preparing N-fluorenylmethoxycarbonyl-L-glutamic acid-1-benzyl ester; (3) preparing S-triphenylmethyl cysteamine; (4) preparing N-fluorenylmethoxycarbonyl-gamma-(S-triphenylmethyl-cysteamine)-L-glutamic acid-alpha-benzyl ester; and (5) preparing N-fluorenylmethoxycarbonyl-gamma-(S-triphenylmethyl-cysteamine)-L-glutamic acid. The method is rapid, high in yield and simple in separation and purification, and the used solvent is environment-friendly and is suitable for mass production.

ANTI-CD3 ANTIBODY FOLATE BIOCONJUGATES AND THEIR USES

Described herein are novel anti-CD3 Folate antibodies and uses thereof in the treatment of diseases or conditions that would benefit from such.

Novel trivalent anti-influenza reagent

We designed and synthesized novel trivalent anti-influenza reagents. Sialyllactose was located at the terminal of each valence which aimed to block each receptor-binding site of the hemagglutinin (HA) trimer on the surface of the virus. Structural analyse

FOLATE-CONJUGATES AND CORRESPONDING METAL-CHELATE COMPLEXES FOR USE IN DIAGNOSTIC IMAGING AND RADIOTHERAPY

The present invention is directed towards novel folate-conjugates of formula I wherein F is a folate or derivative thereof, Z1, Z2, Z3 are independently of each other C or N, S1 to S4 are independentl