200862-22-2Relevant articles and documents
Efficient regiocontrolled synthesis and antimicrobial activity of pyrazoles
Braibante, Mara E. F.,Braibante, Hugo T. S.,Tavares, Luciana De Carvalho,Rohte, Simone F.,Costa, Carla C.,Morel, Ademir F.,Stueker, Caroline Z.,Burrow, Robert A.
, p. 2485 - 2490 (2008/02/13)
A series of 1,5-diphenyl-1H-pyrazol-3-amines, 3-ethoxy-5-phenyl-1H- pyrazole, 5-ethoxy-1,3-diphenyl-1H-pyrazole and 3-ethoxy-1,5-diphenyl-1H- pyrazole were efficiently prepared from the regiocontrolled cyclization of α-oxoketene O,N-acetals and/or β-oxo thioxoesters with hydrazine derivatives using montmorillonite K-10 as solid support with ultrasound. The antimicrobial activity of the heterocyclic compounds was evaluated by direct bioautography test. Georg Thieme Verlag Stuttgart.
Mild synthesis of α-oxoketene O,N-acetals from β-oxothioxo esters and amines
Furukawa, Isao,Fujisawa, Hironori,Abe, Tetsuji,Ohta, Tetsuo
, p. 599 - 606 (2007/10/03)
α-Oxoketene O,N-acetals were prepared from β-oxothiono esters and primary amines in the presence of Methylamine at room temperature within several hours in good yields.