201139-12-0Relevant articles and documents
'Armed-disarmed' glycosidation strategy based on glycosyl donors and acceptors carrying phosphoroamidate as a leaving group: A convergent synthesis of globotriaosylceramide
Hashimoto, Shun-Ichi,Sakamoto, Hiroki,Honda, Takeshi,Abe, Hiroshi,Nakamura, Sei-Ichi,Ikegami, Shiro
, p. 8969 - 8972 (2007/10/03)
A stereocontrolled synthesis of globotriaosylceramide with three different glycosidic linkages has been accomplished by linear and convergent routes exploiting 'armed-disarmed' glycosidation methodology based on glycosyl donors and acceptors carrying tetramethylphosphoroamidate as a leaving group. In particular, the convergent strategy featuring a coupling of a galactosyl(1→4)-galactosyl donor with a glucosylceramide derivative has proven to be extremely efficient.