201547-20-8

Upstream product

• 54314-84-0 1-[(3-bromopropoxy)methyl]-benzene 
• 201547-03-7 3-(5-spiro-2,2-dimethyl-1,3-dioxacyclopentyl)-6-heptyne-1-ol 
• 68654-85-3 5-(trimethylsilyl)pent-4-ynal 
• 201547-19-5 1-t-butyldimethylsilyloxy-3-(5-spiro-2,2-dimethyl-1,3-dioxacyclopentyl)-7-trimethylsilyl-6-heptyne 
• 201547-49-1 2-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-6-trimethylsilanyl-hex-5-yne-1,2-diol 
• 201547-18-4 1-t-butyldimethylsilyloxy-3-methylene-7-trimethylsilyl-6-heptyne 
• 201547-16-2 1-t-butyldimethylsilyloxy-3-oxo-7-trimethylsilyl-6-heptyne 
• 201547-14-0 1-t-butyldimethylsilyloxy-3-hydroxy-7-trimethylsilyl-6-heptyne 
• 201547-11-7 methyl 3-hydroxy-7-(trimethylsilyl)hept-6-ynoate 
• 176797-93-6 7-(trimethylsilyl)hept-6-yne-1,3-diol 
• 13224-84-5 5-trimethylsilanyl-pent-4-yn-1-ol 

Downstream Products

• 201546-99-8 [4-(7-benzyloxy-heptyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-acetaldehyde 
• 201547-22-0 t-butyl 12-benzyloxy-2-pentadecanyl-5-(5-spiro-2,2-dimethyl-1,3-dioxacyclopentyl)-2-dodecenoate 
• 201547-38-8 t-butyl 12-benzyloxy-2-icosanyl-5-(5-spiro-2,2-dimethyl-1,3-dioxacyclopentyl)-2-dodecenoate 
• 201547-21-9 10-benzyloxy-3-(5-spiro-2,2-dimethyl-1,3-dioxacyclopentyl)-1-decanol 

Relevant academic research and scientific papers

Total synthesis of analogs of topostin B, A DNA topoisomerase I inhibitor. Part 3: Improved synthesis of topostin B-1 analogs

Analogs of (E)-topostin B-1 (1a-c) and (Z)-topostin B-1 (2a-c), an inhibitor of mammalian DNA topoisomerase I, have been synthesized in a convenient manner.