Total synthesis of analogs of topostin B, A DNA topoisomerase I inhibitor. Part 3: Improved synthesis of topostin B-1 analogs

DOI: 10.1016/S0040-4020(97)10315-5

Source and publish data:

Tetrahedron p. 551 - 564 (1998)

Update date:2022-08-03

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Authors:

Fujiwara, Hideyasu

Aoyama, Toyohiko

Shioiri, Takayuki

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Article abstract of DOI:10.1016/S0040-4020(97)10315-5

Analogs of (E)-topostin B-1 (1a-c) and (Z)-topostin B-1 (2a-c), an inhibitor of mammalian DNA topoisomerase I, have been synthesized in a convenient manner.

Full text of DOI:10.1016/S0040-4020(97)10315-5

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