20193-21-9

Usage

Uses

Used in Chemical Synthesis:
N-BUTYL-N-PROPYLAMINE is used as a chemical intermediate for the synthesis of various compounds, including pharmaceuticals, agrochemicals, and specialty chemicals. Its unique structure and reactivity make it a valuable building block in the development of new molecules with specific properties.
Used in Catalyst Preparation:
N-BUTYL-N-PROPYLAMINE is used as a pore directing template in the preparation of microporous mixed metal oxides. Its ability to influence the pore size and surface area of these materials makes it an important component in the design of catalysts for various chemical reactions.
Used in Material Science:
N-BUTYL-N-PROPYLAMINE is used in the development of advanced materials, such as microporous mixed metal oxides, due to its impact on their structural properties. These materials have potential applications in gas separation, energy storage, and catalysis.
Used in Research and Development:
N-BUTYL-N-PROPYLAMINE is used as a research compound to study the effects of pore directing templates on the properties of microporous materials. Its use in this context contributes to the advancement of material science and the development of new technologies.

InChI:InChI=1/C7H17N/c1-3-5-7-8-6-4-2/h8H,3-7H2,1-2H3

Upstream product

• 2038-24-6 N-propylidenebutylamine 
• 71-23-8 propan-1-ol 
• 109-73-9 N-butylamine 
• 110-91-8 morpholine 
• 130716-87-9 N-butylidenebutylamine 
• 513-81-5 2,3-dimethyl-buta-1,3-diene 
• 2955-67-1 N-butylpropionamide 
• 109-74-0 propyl cyanide 
• 74-85-1 ethene 
• 201230-82-2 carbon monoxide 
• 107-10-8 propylamine 
• 123-72-8 butyraldehyde 
• 855339-41-2 benzyl-butyl-propyl-amine 
• 7707-71-3 butylidene-propyl-amine 

Downstream Products

• 141328-60-1 N-n-propyl-N-n-butyl 2-phenylacetamide 
• 1053256-23-7 (4S,5R,6R)-5-Acetylamino-4-tert-butoxycarbonylamino-6-(butyl-propyl-carbamoyl)-5,6-dihydro-4H-pyran-2-carboxylic acid benzhydryl ester 
• 136722-37-7 7-(Butyl-propyl-amino)-1-cyclohexyl-1-hydroxy-1-phenyl-hept-5-yn-2-one 
• 7707-71-3 butylidene-propyl-amine 
• 25413-64-3 N-Nitroso-N-butyl-N-propylamine 
• 24551-99-3 N-methyl-N-propylbutylamine 
• 502767-31-9 N₂-butyl-6-chloro-N₄-(3-chloro-4-methoxy-phenyl)-N₂-propyl-[1,3,5]triazine-2,4-diamine 

Relevant academic research and scientific papers

Selective one-pot synthesis of asymmetric secondary amines via N-alkylation of nitriles with alcohols

The synthesis of asymmetric secondary amines (ASA) is commonly achieved by N-alkylation of primary amines with alcohols. Here, we investigated the ASA synthesis via the direct amination of alcohols with nitriles, which avoids the synthesis, separation and purification of the primary amines in a first step. Specifically, the ASA synthesis via N-alkylation of butyronitrile (BN) with primary (n-propanol, iso-butanol and n-octanol) and secondary (2‐propanol, 2‐butanol and 2‐octanol) alcohols was studied on SiO2-supported Co, Ni and Ru catalysts. Competitive BN hydrogenation‐condensation reactions formed dibutylamine (the symmetric secondary amine) and tertiary amines as main secondary products. On Co/SiO2, the ASA selectivities for BN/primary alcohol reactions were between 49 and 58% at complete BN conversion, forming dibutylamine and tertiary amines as byproducts. For BN/secondary alcohol reactions, Co/SiO2 formed selectively (ASA + dibutylamine) mixtures containing 78–85% of ASA, thereby showing that the alcohol amination with nitriles is an attractive alternative route for the synthesis of valuable asymmetric secondary amines.

Mild Hydrogenation of Amides to Amines over a Platinum-Vanadium Bimetallic Catalyst

Hydrogenation of amides to amines is an important reaction, but the need for high temperatures and H2 pressures is a problem. Catalysts that are effective under mild reaction conditions, that is, lower than 30 bar H2 and 70 °C, have not yet been reported. Here, the mild hydrogenation of amides was achieved for the first time by using a Pt-V bimetallic catalyst. Amide hydrogenation, at either 1 bar H2 at 70 °C or 5 bar H2 at room temperature was achieved using the bimetallic catalyst. The mild reaction conditions enable highly selective hydrogenation of various amides to the corresponding amines, while inhibiting arene hydrogenation. Catalyst characterization showed that the origin of the catalytic activity for the bimetallic catalyst is the oxophilic V-decorated Pt nanoparticles, which are 2 nm in diameter.

Catalytic hydrogenation of amides to amines under mild conditions

Under (not so much) pressure: A general method for the hydrogenation of tertiary and secondary amides to amines with excellent selectivity using a bimetallic Pd-Re catalyst has been developed. The reaction proceeds under low pressure and comparatively low temperature. This method provides organic chemists with a simple and reliable tool for the synthesis of amines. Copyright

ELECTROCHEMICAL REDUCTIVE AMINATION. II. AMINATION OF ALIPHATIC ALDEHYDES WITH PRIMARY AMINES

The formation of a secondary amine by the electrolysis of an aqueous solution containing an aldehyde and a primary amine was studied.The formation of the secondary amines passes through the intermediate stage of an aldimine.The highest yield of secondary amine is attained at a molar ratio of primary amine to aldehyde of 1.2:1.As electrode material lead, cadmium, zinc, and copper may be used.As supporting electrolyte a phosphate buffer with a pH close to the pKa of the primary amine is recommended.By the method developed 32 amines with various structures were synthesized.

PHOSPHONIUM DIAZA-DIYLIDS AND AZA-YLDIID AS NEW AND EFFICIENT REAGENTS FOR PRIMARY AND SECONDARY AMINES SYNTHESIS

Metallated aminophosphonium ylids, diaza-diylids and aza-yldiid, are investigated as reagents for primary and secondary amines synthesis.

The selective preparation of n-propylamines by the rhodium catalysed reaction of ethylene and syngas with alkylamines

The aminoethylation of ethylene with a primary amine has been shown to provide a highly selective route to n-propylamines; the rhodium catalysed reaction of n-propylamine with ethylene and syngas (2/1, H2/CO) affords di-n-propylamine with 98percent selectivity (with respect to ethylene).The reaction of amines of the type RR1NH with the ethylene/syngas mixture and a rhodium catalyst provides a highly selective and general route to the n-propylamines RR1NPr (R=Pr, R1=H; R=t-Bu, R1=H; R=n-Bu, R1=H; R=C8H17, R1=H, R=R1=Pr; R=HOCH2Ch2, R1=H, and R=PhCH(OH)CH2, R1=H).

Nonylamines

New nonadienylamines, nonatrienylamines and nonylamines are described, as well as a new process for their manufacture by reacting a 1,3-diolefine with a Schiff's base in the presence of certain nickel catalysts. The new compounds are suitable for combating micro-organisms, for example in the protection of materials.

1,4-Dithiino[2,3-c; 6,5-c']diisothiazole and related compounds

The compound 3,7-dicyano-1,4-dithiino[2,3-c; 6,5-c']diisothiazole is prepared by reacting either tetracyano-1,4-dithiin or 4,5-dicyano-1,3-dithiolen-2-one with sulfur in 1,2-dimethoxyethane at a temperature of 50°-280° C in the presence of a basic catalyst. The diisothiazole can be converted to derivatives with various utilities, e.g., as fluorescent brighteners.