202197-73-7

Basic information

• Product Name: 3,4-DIHYDRO-4-OXOQUINAZOLINE-7-CARBOXYLIC ACID
• Synonyms: 3,4-DIHYDRO-4-OXOQUINAZOLINE-7-CARBOXYLIC ACID;7-CARBOXY-4-QUINAZOLONE;7-Quinazolinecarboxylic acid, 3,4-dihydro-4-oxo-;3,4-Dihydro-4-oxo-7-quinazolinecarboxylic acid;4-oxo-3,4-dihydroquinazoline-7-carboxylic acid;3,4-DEHYDRO-4-OXO-7-QUINZOLINECARBOXYLIC ACID;3,4-Dihydro-4-oxoquinazoline-7-carboxylic acid, >=97%;4-Oxo-1,4-dihydro-quinazoline-7-carboxylic acid
• CAS NO: 202197-73-7
• Molecular Formula: C₉H₆N₂O₃
• Molecular Weight: 190.16
• Mol File: 202197-73-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: >300 °C
• Boiling Point: 540.598 °C at 760 mmHg
• Flash Point: 280.744 °C
• Appearance: /
• Density: 1.562 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.74±0.20(Predicted)
• CAS DataBase Reference: 3,4-DIHYDRO-4-OXOQUINAZOLINE-7-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DIHYDRO-4-OXOQUINAZOLINE-7-CARBOXYLIC ACID(202197-73-7)
• EPA Substance Registry System: 3,4-DIHYDRO-4-OXOQUINAZOLINE-7-CARBOXYLIC ACID(202197-73-7)

Safety Data

• Hazardous Substances Data: 202197-73-7(Hazardous Substances Data)

Usage

General Description

3,4-Dihydro-4-oxoquinazoline-7-carboxylic acid is a chemical compound with the molecular formula C9H7N3O3. It is a derivative of quinazoline and carboxylic acid, and it is commonly used in pharmaceutical research and as a building block in the synthesis of various drugs. 3,4-DIHYDRO-4-OXOQUINAZOLINE-7-CARBOXYLIC ACID has been studied for its potential properties in treating diseases such as cancer and inflammation. Its chemical structure and properties make it a valuable tool in medicinal chemistry and drug discovery efforts.

Upstream product

• 10312-55-7 3-aminoterephthalic acid 
• 77287-34-4 formamide 
• 2050-44-4 N-(2,5-dimethylphenyl)acetamide 
• 99185-32-7 2-acetamidoterephthalic acid 

Downstream Products

• 942507-89-3 4-chloroquinazoline-7-carboxylic acid 
• 758710-78-0 4-chloroquinazoline-7-carboxylic acid chloride 
• 313535-84-1 methyl 4-oxo-3,4-dihydroquinazoline-7-carboxylate 
• 887128-72-5 {3-(4-chloro-phenyl)-3-[(4-oxo-3,4-dihydro-quinazoline-7-carbonyl)-amino]-propyl}-carbamic acid benzyl ester 

Relevant articles and documents

IDENTIFICATION AND USE OF ERK5 INHIBITORS

The present invention covers heterocyclic compounds of general formula (I) in which T, U, Y, Z, R1 and R3 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of cancer disorders, as a sole agent or in combination with other active ingredients.

CHEMICAL COMPOUNDS

The invention relates to chemical compounds of the formula (I) or pharmaceutically acceptable salts thereof, which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.

NOVEL BICYCLIC AROMATIC COMPOUNDS, THE PRODUCTION AND USE THEREOF IN THE FORM OF DRUGS

The invention relates to novel aromatic bicycle compounds of formula (I), wherein Ar, X, Y and R1-R3 are such as specified in a claim 1. Said invention also relates to the tautomers, enantiomers, diasteriomers, mixtures, pro-drugs an