202199-06-2Relevant academic research and scientific papers
Design and development of multitarget-directed N-Benzylpiperidine analogs as potential candidates for the treatment of Alzheimer's disease
Sharma, Piyoosh,Tripathi, Avanish,Tripathi, Prabhash Nath,Prajapati, Santosh Kumar,Seth, Ankit,Tripathi, Manish Kumar,Srivastava, Pavan,Tiwari, Vinod,Krishnamurthy, Sairam,Shrivastava, Sushant Kumar
, p. 510 - 524 (2019)
The multitarget-directed strategy offers an effective and promising paradigm to treat the complex neurodegenerative disorder, such as Alzheimer's disease (AD). Herein, a series of N-benzylpiperidine analogs (17–31 and 32–46) were designed and synthesized
AZACYCLIC COMPOUNDS
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Paragraph 0295, (2015/11/09)
Compounds and methods are provided for the treatment of disease conditions in which modification of serotonergic receptor activity has a beneficial effect. In the method, an effective amount of a compound is adminstered to a patient in need of such treatment.
USE OF 4-AMINO-PIPERIDINES FOR TREATING SLEEP DISORDERS
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Page/Page column 75-76, (2010/11/28)
Inverse agonists and antagonists of serotonin receptors are disclosed for use in treating sleep disorders such as insomnia, and specifically sleep maintenance insomnia. The compound increase slow wave sleep, decrease the number of awakenings after sleep onset, and decrease the time awake after sleep onset.
Azacyclic compounds
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, (2008/06/13)
Compounds and methods are provided for the treatment of disease conditions in which modification of serotonergic receptor activity has a beneficial effect. In the method, an effective amount of a compound is adminstered to a patient in need of such treatment.
