202344-74-9

Upstream product

• 96502-90-8 acetic acid 2,4-dimethoxy-3-methyl-phenyl ester 
• 5673-07-4 2,6-dimethoxytoluene 
• 19676-67-6 2,4-dimethoxy-3-methylphenol 
• 60512-80-3 2′,4′-dimethoxy-3′-methylacetophenone 
• 2207-57-0 2-methoxy-3-methyl-1,4-benzoquinone 
• 62-53-3 aniline 

Downstream Products

• 115920-44-0 carbazomycin G 

Relevant academic research and scientific papers

Indoloquinones, Part 5: Palladium-catalyzed total synthesis of the potent lipid peroxidation inhibitor carbazoquinocin C

The efficient palladium-catalyzed oxidative coupling of an anilinoquinone and subsequent regioselective introduction of the heptyl side chain provide the antioxidative substance carbazoquinocin C in four steps and 36% overall yield from aniline.

Transition metals in organic synthesis - Part 83#: Synthesis and pharmacological potential of carbazoles

A series of carbazole derivatives with promising pharmacological properties has been prepared using either an iron-mediated or a palladium-catalyzed synthetic approach. The carbazole alkaloids carbazoquinocin C, carbazomadurin A and B, epocarbazolin A and

Indoloquinones, part 7. Total synthesis of the potent lipid peroxidation inhibitor carbazoquinocin C by an intramolecular palladium-catalyzed oxidative coupling of an anilino-1,4-benzoquinone

A highly efficient total synthesis of the potent lipid peroxidation inhibitor carbazoquinocin C is presented. The key-step is a palladium(II)-catalyzed oxidative cyclization of an anilino-1,4-benzoquinone to a carbazole-1,4-quinone which proceeds in up to 91% yield. Using this approach the natural product is obtained in four steps and 39% overall yield starting from aniline.

Palladium-catalyzed total synthesis of the antibiotic carbazole alkaloids carbazomycin G and H

A highly efficient palladium-catalyzed synthesis affords carbazole-1,4-quinones which can be transformed directly into the carbazomycins G and H and are shown to represent precursors for several other biologically active carbazole alkaloids.