2027-19-2

Basic information

• Product Name: 2-N-PROPYLNAPHTHALENE
• Synonyms: 2-N-PROPYLNAPHTHALENE;3-(2-Naphtyl)propane
• CAS NO: 2027-19-2
• Molecular Formula: C₁₃H₁₄
• Molecular Weight: 170.25
• Mol File: 2027-19-2.mol
• Article Data: 7

Chemical Properties

• Melting Point: -2.99°C
• Boiling Point: 274.85°C
• Flash Point: 118.9 °C
• Appearance: /
• Density: 0.9730
• Vapor Pressure: 0.00862mmHg at 25°C
• Refractive Index: 1.5850
• CAS DataBase Reference: 2-N-PROPYLNAPHTHALENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-N-PROPYLNAPHTHALENE(2027-19-2)
• EPA Substance Registry System: 2-N-PROPYLNAPHTHALENE(2027-19-2)

Safety Data

• Hazardous Substances Data: 2027-19-2(Hazardous Substances Data)

Usage

General Description

2-N-PROPYLNAPHTHALENE is a chemical compound with the molecular formula C18H16. It is a colorless liquid with a faint odor, and is commonly used as a fragrance ingredient in various cosmetic and personal care products. It is also used in the manufacturing of adhesives, coatings, and polymers. Additionally, 2-N-PROPYLNAPHTHALENE is a known environmental contaminant and can be harmful if ingested or inhaled in large quantities. It is important to handle this chemical with caution and follow proper safety guidelines when working with it.

InChI:InChI=1/C13H14/c1-2-5-11-8-9-12-6-3-4-7-13(12)10-11/h3-4,6-10H,2,5H2,1H3

Upstream product

• 93-04-9 2-Methoxynaphthalene 
• 2397-67-3 triisopropylaluminium 
• 7498-57-9 2-naphthaleneacetonitrile 
• 135-19-3 β-naphthol 
• 1068-55-9 isopropylmagnesium chloride 
• 1068-56-0 isopropylmagnesium iodide 
• 1260224-49-4 (R)-2-(1-methoxypropyl)naphthalene 
• 693-25-4 n-pentylmagnesium bromide 
• 557-20-0 diethylzinc 
• 1442649-71-9 1-(naphthalen-2-yl)propyl 2-mercapto-2-methylpropanoate 
• 1442649-70-8 1-(naphthalen-2-yl)propyl 2-mercaptoacetate 
• 627-19-0 1-Pentyne 
• 59046-72-9 o-(phenylethynyl)benzaldehyde 
• 124-38-9 carbon dioxide 

Downstream Products

• 42775-77-9 6-Propyl-tetralin 
• 66324-84-3 2-n-propyltetralin 

Relevant articles and documents

Tetraethylphosphorodiamidate-Directed Metalation Group: Directed Ortho and Remote Metalation, Cross Coupling, and Remote Phospha Anionic Fries Rearrangement Reactions

The linked directed ortho and remote metalation (DoM and DreM) and cross-coupling reactions of aryl phosphorodiamidates (Ar-OP(O)(NEt2)2) is reported. The o-iodo and o-boronato aryl tetraethylphosphorodiamidates 3, prepared by DoM, undergo orthogonal Ni- and Pd-catalyzed Suzuki-Miyaura cross coupling to furnish biaryls 4 and 5 in good to excellent yields. Silicon group protection of biaryl 4 via DoM followed by previously unobserved DreM phospha anionic Fries rearrangement affords biaryls 11 which, under acidic conditions, furnish oxaphosphorine oxides 12.

Nickel-catalyzed alkylative cross-coupling of anisoles with grignard reagents via C-O bond activation

We report nickel-catalyzed cross-coupling of methoxyarenes with alkylmagnesium halides, in which a methoxy group is eliminated. A wide range of alkyl groups, including those bearing β-hydrogens, can be introduced directly at the ipso position of anisole derivatives. We demonstrate that the robustness of a methoxy group allows this alkylation protocol to be used to synthesize elaborate molecules by combining it with traditional cross-coupling reactions or oxidative transformation. The success of this method is dependent on the use of alkylmagnesium iodides, but not chlorides or bromides, which highlights the importance of the halide used in developing catalytic reactions using Grignard reagents.

Stereospecific nickel-catalyzed cross-coupling reactions of alkyl grignard reagents and identification of selective anti-breast-cancer agents

Alkyl Grignard reagents that contain β-hydrogen atoms were used in a stereospecific nickel-catalyzed cross-coupling reaction to form C(sp 3)-C(sp3) bonds. Aryl Grignard reagents were also utilized to synthesize 1,1-diarylalkanes. Sev