202822-39-7

Upstream product

• 455-14-1 4-trifluoromethylphenylamine 
• 68216-06-8 ethyl 5-chloro-2-methoxybenzoate 
• 29568-33-0 2-methoxy-5-chlorobenzoyl chloride 

Downstream Products

• 1408319-20-9 C₁₅H₁₁ClF₃NOS 
• 202822-49-9 5-(5-Chloro-2-methoxyphenyl)-4-[4-(trifluoromethyl)phenyl]-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 202822-55-7 2-(5-chloro-2-methoxyphenyl)-1-[4-(trifluoromethyl)phenyl]-1H-imidazole 

Relevant academic research and scientific papers

4,5-Diphenyltriazol-3-ones: Openers of large-conductance Ca2+-activated potassium (maxi-K) channels

A series of diphenyl-substituted heterocycles were synthesized and evaluated by electrophysiological techniques as openers of the cloned mammalian large-conductance, Ca2+-activated potassium (maxi-K) channel. The series was designed from deannu

Aminolysis of esters or lactones promoted by NaHMDS-A general and efficient method for the preparation of N-aryl amides

An efficient method for the preparation of N-aryl amides from anilines, esters or lactones promoted by NaHMDS is described. Advantages of this new method include high yields and mild reaction conditions which tolerate functional groups such as ketones and halides.