203259-23-8Relevant academic research and scientific papers
Concise syntheses of acromelic acid A and allo-acromelic acid A
Baldwin, Jack E.,Fryer, Andrew M.,Pritchard, Gareth J.,Spyvee, Mark R.,Whitehead, Roger C.,Wood, Mark E.
, p. 707 - 710 (2007/10/03)
Acromelic acid A 1 and allo-acromelic acid A 12 were synthesised in a biomimetic fashion. An oxidative cleavage-recyclisation strategy was used to construct the requisite C-4 pyridone from an intermediate catechol.
A biomimetic approach to the pyridone rings of the acromelic acids: A concise synthesis of acromelic acid a and an approach to acromelic acid B.
Baldwin, Jack E.,Fryer, Andrew M.,Pritchard, Gareth J.,Spyvee, Mark R.,Whitehead, Roger C.,Wood, Mark E.
, p. 7465 - 7484 (2007/10/03)
The syntheses of acromelic acid A 1, allo-acromelic acid A 19 and an approach towards acromelic acid B 2 are described. Palladium (0) catalysed cross-coupling reactions were used to generate C-4 catechol precursors and formation of the pyridone rings was investigated using a biomimetic oxidative cleavage - recyclisation strategy.
