55020-67-2

Upstream product

• 934-00-9 3-methocycatechol 
• 100-39-0 benzyl bromide 

Downstream Products

• 210824-68-3 3,4-dibenzyloxy-2-methoxy-1-bromobenzene 
• 203259-23-8 2,3-dibenzyloxy-4-methoxy-1-bromobenzene 
• 858218-65-2 2-benzyloxy-6-methoxy-hydroquinone 
• 203259-13-6 (2S,3S)-1-Benzoyl-4-(2,3-bis-benzyloxy-4-methoxy-phenyl)-3-tert-butoxycarbonylmethyl-2,3-dihydro-1H-pyrrole-2-carboxylic acid methyl ester 
• 210824-83-2 (2S,3S)-1-Benzoyl-4-(3,4-bis-benzyloxy-2-methoxy-phenyl)-3-tert-butoxycarbonylmethyl-2,3-dihydro-1H-pyrrole-2-carboxylic acid methyl ester 
• 210824-85-4 [(2S,3S)-1-Benzoyl-4-(3,4-bis-benzyloxy-2-methoxy-phenyl)-2-hydroxymethyl-2,3-dihydro-1H-pyrrol-3-yl]-acetic acid tert-butyl ester 
• 203259-18-1 [(2S,3S)-1-Benzoyl-4-(2,3-bis-benzyloxy-4-methoxy-phenyl)-2-hydroxymethyl-2,3-dihydro-1H-pyrrol-3-yl]-acetic acid tert-butyl ester 
• 854050-00-3 2-benzyloxy-6-methoxy-[1,4]benzoquinone 

Relevant academic research and scientific papers

A biomimetic approach to the pyridone rings of the acromelic acids: A concise synthesis of acromelic acid a and an approach to acromelic acid B.

The syntheses of acromelic acid A 1, allo-acromelic acid A 19 and an approach towards acromelic acid B 2 are described. Palladium (0) catalysed cross-coupling reactions were used to generate C-4 catechol precursors and formation of the pyridone rings was investigated using a biomimetic oxidative cleavage - recyclisation strategy.