20328-66-9

Basic information

• Product Name: 1-FURAN-2-YL-2,2-DIHYDROXY-ETHANONE
• Synonyms: 1-(2-furanyl)-2,2-dihydroxyEthanone;2-FURANYLGLYOXAL HYDRATE;1-FURAN-2-YL-2,2-DIHYDROXY-ETHANONE;Furan-2-ylglyoxal hydrate;1-(furan-2-yl)-2,2-dihydroxyethan-1-one
• CAS NO: 20328-66-9
• Molecular Formula: C₆H₆O₄
• Molecular Weight: 142.11
• Mol File: 20328-66-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 261.5 °C at 760 mmHg
• Flash Point: 112 °C
• Appearance: /
• Density: 1.433 g/cm³
• Vapor Pressure: 0.00581mmHg at 25°C
• Refractive Index: 1.55
• CAS DataBase Reference: 1-FURAN-2-YL-2,2-DIHYDROXY-ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-FURAN-2-YL-2,2-DIHYDROXY-ETHANONE(20328-66-9)
• EPA Substance Registry System: 1-FURAN-2-YL-2,2-DIHYDROXY-ETHANONE(20328-66-9)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 20328-66-9(Hazardous Substances Data)

Usage

Description

1-Furan-2-yl-2,2-dihydroxy-ethanone, commonly known as furfurylidene glycerol, is a chemical compound with the molecular formula C7H8O4. It is a yellowish liquid characterized by its pleasant odor and taste, making it a valuable ingredient in various industries.

Uses

Used in Food Industry:
1-Furan-2-yl-2,2-dihydroxy-ethanone is used as a flavoring agent for its pleasant odor and taste, enhancing the sensory experience of food products.
Used in Pharmaceutical Industry:
1-Furan-2-yl-2,2-dihydroxy-ethanone is utilized in the production of pharmaceuticals, likely due to its anti-inflammatory and antioxidant properties, which may contribute to the development of therapeutic agents.
Used in Fragrance Industry:
1-Furan-2-yl-2,2-dihydroxy-ethanone is employed as a component in fragrances, capitalizing on its agreeable scent to create appealing olfactory experiences in various products.
Used as a Solvent in Industrial Applications:
1-Furan-2-yl-2,2-dihydroxy-ethanone serves as a solvent in a range of industrial processes, leveraging its chemical properties to facilitate reactions or dissolve substances.
Used in Research for Natural Preservatives:
1-Furan-2-yl-2,2-dihydroxy-ethanone is being studied for its potential as a natural preservative, indicating its possible use in extending the shelf life of products while minimizing the use of synthetic preservatives.
It is important to handle 1-Furan-2-yl-2,2-dihydroxy-ethanone with care due to its potential to cause irritation to the skin, eyes, and respiratory system upon contact.

InChI:InChI=1/C6H6O4/c7-5(6(8)9)4-2-1-3-10-4/h1-3,6,8-9H

Upstream product

• 17090-71-0 furan-2-yl-oxo-acetaldehyde 
• 59896-20-7 cortalcerone 
• 1192-62-7 1-(2-furyl)-1-ethanone 
• 527-69-5 2-furancarbonyl chloride 
• 21443-46-9 2-diazoacetylfuran 

Downstream Products

• 19377-73-2 (rac)-2-(furan-2-yl)-2-hydroxyacetic acid 
• 494-21-3 2-furan-2-yl-quinoxaline 
• 82619-62-3 2-Hydroxy-5-(2'-furyl)pyrazine 
• 1088991-16-5 C₁₅H₁₂O₃S 
• 1088991-15-4 C₁₅H₁₂O₃S 
• 82619-63-4 2-chloro-5-furan-2-yl-pyrazine 

Relevant articles and documents

Synthesis and X-ray Characterization of Alkali Metal 2-Acyl-1,1,3,3-tetracyanopropenides

A novel route for synthesis of 2-acyl-1,1,3,3-tetracyanopropenides (ATCN) salts in high yields and excellent purities starting from readily available methyl ketones, malononitrile, bromine, and alkali metal acetates is reported. The starting aryl(heteroaryl) methyl ketones were oxidized to the corresponding α-ketoaldehydes by new a DMSO-NaBr-H2SO4 oxidation system in yields up to 90% within a short reaction time of 8-10 min. The subsequent stages of ATCN preparation are realized in aqueous media without use of any toxic solvents, in accordance with principle 5 of "green chemistry". Lithium, sodium, potassium, rubidium, and cesium 2-benzoyl-1,1,3,3-tetracyanopropenides were characterized by X-ray diffraction analysis. These salts show a good potential for synthesis of five- and six-membered heterocycles and may serve as potentially useful ligands in coordination and supramolecular chemistry.

Metal-free dual sp3 C-H functionalization: I2- promoted domino oxidative cyclization to construct 2,5-disubstituted oxazoles

An I2-promoted sp3 C-H functionalization has been developed for the synthesis of 2,5-disubstituted oxazoles from easily available methyl ketones and benzylamines without any metal and peroxide catalyst. This domino oxidative cyclization process involves the cleavage of C-H bond and the formation of C-N, C-O bonds.

Oxidation of diazo compounds by dimethyl dioxirane: An extremely mild and efficient method for the preparation of labile α-oxo-aldehydes

A novel method for the preparation of α-oxo-aldehydes by dimethyl dioxirane oxidation of α-diazoketones is described. The procedure is particularly useful when the desired compound cannot be purified by chromatography or distillation: the by-products (ace