20332-16-5

Basic information

• Product Name: 6-AMINO-1,3-BENZODIOXOLE-5-CARBOXYLIC ACID
• Synonyms: 6-AMinobenzo[d][1,3]dioxole-5-carboxylic acid;1,3-Benzodioxole-5-carboxylicacid, 6-aMino-
• CAS NO: 20332-16-5
• Molecular Formula: C₈H₇NO₄
• Molecular Weight: 181.15
• Mol File: 20332-16-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 387.9°Cat760mmHg
• Flash Point: 188.4°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 1.04E-06mmHg at 25°C
• Refractive Index: 1.679
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 6-AMINO-1,3-BENZODIOXOLE-5-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 6-AMINO-1,3-BENZODIOXOLE-5-CARBOXYLIC ACID(20332-16-5)
• EPA Substance Registry System: 6-AMINO-1,3-BENZODIOXOLE-5-CARBOXYLIC ACID(20332-16-5)

Safety Data

• Hazardous Substances Data: 20332-16-5(Hazardous Substances Data)

Usage

General Description

6-Amino-1,3-benzodioxole-5-carboxylic acid is a chemical compound that belongs to the family of benzodioxole derivatives. It is a white to off-white crystalline powder and is used in the synthesis of pharmaceutical compounds and research applications. 6-AMINO-1,3-BENZODIOXOLE-5-CARBOXYLIC ACID has a molecular formula of C9H7NO4 and a molecular weight of 189.16 g/mol. It has a high solubility in water and is stable under normal storage conditions. 6-Amino-1,3-benzodioxole-5-carboxylic acid is also known for its potential pharmacological activities and may have uses in the development of drugs and therapies.

InChI:InChI=1/C8H7NO4/c9-5-2-7-6(12-3-13-7)1-4(5)8(10)11/h1-2H,3,9H2,(H,10,11)

Upstream product

• 716-32-5 6-nitrobenzo[d][1,3]dioxole-5-carboxylic acid 
• 721-00-6 methyl 6-nitrobenzo[d][1,3]dioxole-5-carboxylate 
• 40680-63-5 methyl 6-aminobenzo[d][1,3]dioxole-5-carboxylate 
• 326-56-7 methyl 3,4-methylenedioxybenzoate 
• 94-53-1 Piperonylic acid 
• 23126-68-3 6-amino-benzo[1,3]dioxole-5-carbaldehyde 
• 7647-01-0 hydrogenchloride 
• 267-54-9 3-methyl[1,3]dioxolo[4’,5’:4,5]benzisoxazoleb 
• 120-57-0 piperonal 
• 712-97-0 6-nitro-1,3-benzodioxole-5-carbaldehyde 

Downstream Products

• 28857-37-6 (6-aminobenzo[d][1,3]dioxol-5-yl)methanol 
• 886493-57-8 C₁₅H₁₅NO₅S 
• 20197-55-1 6,8-dichloro-2H-[1,3]dioxolo[4,5-g]quinazoline 
• 34060-22-5 N-methyl-3,4-(methylenedioxy)aniline 
• 548-31-2 oxynitidine 
• 848474-61-3 6-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-benzo[1,3]dioxole-5-carboxylic acid 

Relevant articles and documents

The synthesis of some 2,4-disubstituted derivatives of quinolone-3-carboxylic acids and carbonitriles

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Condensation of anthranilic acids with pyridines to furnish pyridoquinazolones via pyridine dearomatization

The unprecedented carbodiimide-mediated condensation between pyridines and anthranilic acids via pyridine dearomatization at room temperature has been developed to provide a straightforward approach to pyridoquinazolones. The value of this approach has further been demonstrated by its application to one-step, gram-scale syntheses of a series of pyridoquinazolone-based natural products and their analogues from readily available starting materials.

FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF

AbstractNovel compounds of the following formula (I) and pharmacologically acceptable salt and esters thereof can modulate LXR function and as a result show excellent anti-arteriosclerotic and anti-inflammatory activity:wherein:A represents aryl or heteroaryl;R1, R2 and R3 are the same or different and each represents hydrogen, hydroxyl, nitro, cyano, amino, halogen, carboxy, carbamoyl, mercapto, alkyl, haloalkyl, alkylcarbonyloxy, alkoxy, alkylthio, alkylsulfinyl, alkylsulfonyl, alkylamino, dialkylamino, alkylcarbonylamino, N-(alkylcarbonyl)-N-(alkyl)amino, alkoxycarbonylamino, N-(alkoxycarbonyl)-N-(alkyl)amino, alkylsulfonylamino, N-(alkylsulfonyl)-N-(alkyl)amino, haloalkylsulfonylamino, N-(haloalkylsulfonyl)-N-(alkyl)amino, alkylcarbonyl, alkoxycarbonyl, alkylaminocarbonyl or dialkylaminocarbonyl group, or R1 and R2 together are alkylenedioxy;R4 and R5 are the same or different and each represents hydrogen, hydroxyl, amino, halogen, mercapto, alkyl, haloalkyl, alkoxy, alkoxycarbonyl or alkylthio;X represents hydrogen, hydroxyl, halogen, alkoxy or haloalkoxy; andY represents an optionally substituted alkyl, cycloalkyl, heterocyclyl, aryl, cycloalkylalkyl, heterocyclylalkyl or aralkyl group.