203446-11-1Relevant academic research and scientific papers
Preparation and properties of enantiomerically pure Nα-tritylamino acid fluorides
Karygiannis, Georgios,Athanassopoulos, Costas,Mamos, Petros,Karamanos, Nikolaos,Papaioannou, Dionissios,Francis, George W.
, p. 1144 - 1150 (2007/10/03)
Cyanuric fluoride-mediated fluorination of chiral Nα-tritylamino acids leads to the corresponding acyl fluorides which are powerful acylating agents for peptide synthesis. The acyl fluorides react with NaBH4, the stabilized phosphorane Ph3P=C(Me)CO2Me and Ruppert's reagent providing access to enantiomerically pure tritylamino alcohols, alkenes and trifluoromethyl ketones, respectively. Acta Chemica Scandinavica 1998.
Aminolysis of N-tritylamino acid benzotriazolyl esters with concentrated aqueous amines and its applications in synthesis
Mamos, Petros,Dalatsis, Elias,Athanassopoulos, Costas,Balayiannis, Georgios,Papaioannou, Dionissios,Francis, George W.
, p. 227 - 231 (2007/10/03)
Aminolysis of (S)-N-tritylamino acid benzotriazolyl esters with concentrated aqueous amines produces high yields of the corresponding amides which can be readily detritylated with p-toluensulfonic acid or reduced with lithium aluminium hydride to provide chiral ethane- 1,2-diamine derivatives. Acta Chemica Scandinavica 1998.
