20349-86-4

Usage

Uses

Used in Pharmaceutical Industry:
Benzenepropanoic acid, 2-hydroxy-b-oxo-, methyl ester is used as an intermediate in the synthesis of various pharmaceuticals. Its potential antioxidant and anti-inflammatory properties make it a valuable candidate for research in the development of new drugs and healthcare products.
Used in Fragrance Industry:
Benzenepropanoic acid, 2-hydroxy-b-oxo-, methyl ester is used as a fragrance ingredient in personal care products and cosmetics. Its aromatic properties contribute to the pleasant scent of these products, enhancing their appeal to consumers.
Used in Food Industry:
As a methyl ester, Benzenepropanoic acid, 2-hydroxy-b-oxo-, methyl ester is used as a flavoring agent in food products. Its ability to impart a unique taste and aroma makes it a valuable addition to the flavor profile of various food items.
Safety Precautions:
When handling Benzenepropanoic acid, 2-hydroxy-b-oxo-, methyl ester, it is important to take necessary safety measures. The chemical can cause skin and eye irritation, so it should only be used in well-ventilated areas and with proper personal protective equipment.

Upstream product

• 102-52-3 malonaldehydebis(dimethylacetal) 
• 102342-54-1 1,3,5-tris(trimethylsiloxy)-1-methoxyhexa-1,3,5-triene 
• 118-93-4 o-hydroxyacetophenone 
• 616-38-6 carbonic acid dimethyl ester 
• 425686-45-9 methyl 3-(2-hydroxyphenyl)propiolate 
• 533-58-4 2-Iodophenol 

Downstream Products

• 4139-73-5 4-hydroxy-3-propanoyl-2H-1-benzopyran-2-one 
• 129410-02-2 methyl 2-ethyl-4-oxo-4H-1-benzopyran-3-carboxylate 
• 132018-07-6 2-(4-bromophenyl)-3-(methoxycarbonyl)-4H-benzopyran-4-one 
• 132018-05-4 2-(3,4-dimethoxyphenyl)-3-(methoxycarbonyl)-4H-benzopyran-4-one 
• 51751-37-2 2-Methyl-4-oxo-4H-<1>benzopyran-3-carboxylic acid 
• 1207514-79-1 (E)-methyl 2-(2-hydroxybenzoyl)-3-phenylacrylate 
• 51751-33-8 methyl 2-methylchromone-3-carboxylate 
• 132018-27-0 4-Oxo-2-[4-(3,4,5-trimethoxy-benzoylamino)-phenyl]-4H-chromene-3-carboxylic acid methyl ester 
• 119563-94-9 2-(3,4,5-trimethoxyphenyl)-4-oxo-4H-benzopyran-3-carboxylic acid 
• 132018-18-9 2-(4-nitrophenyl)-4-oxo-4H-benzopyran-3-carboxylic acid 
• 132018-16-7 2-(3,5-dimethoxyphenyl)-4-oxo-4H-benzopyran-3-carboxylic acid 
• 119607-27-1 2-(3,4-dimethoxyphenyl)-4-oxo-4H-benzopyran-3-carboxylic acid 
• 132018-23-6 2-(4-hydroxyphenyl)-3-(methoxycarbonyl)-4H-benzopyran-4-one 
• 132018-26-9 2-(4-aminophenyl)-3-(methoxycarbonyl)-4H-benzopyran-4-one 

Relevant academic research and scientific papers

Studies toward the Total Synthesis of Arylnaphthalene Lignans via a Photo-Dehydro-Diels-Alder (PDDA) Reaction

An efficient method for the preparation of arylnaphthalene lignans (ANLs) was developed, which is based on the Photo-Dehydro-Diels-Alder (PDDA) reaction. While intermolecular PDDA reactions turned out to be inefficient, the intramolecular variant using suberic acid as tether linking two aryl propiolic esters smoothly provided naphthalenophanes. The irradiations were performed with a previously developed annular continuous-flow reactor and UVB lamps. In this way, the natural products Alashinol D, Taiwanin C, and an unnamed ANL could be prepared.

Synthesis and Protein-Tyrosine Kinase Inhibitory Activities of Flavanoid Analogues

Treatment of o-hydroxyacetophenones 2a-e with excess lithium bis(trimethylsilyl)amide followed by dialkyl carbonates gave 3-(2-hydroxyaryl)-3-oxopropanoates 3a-e.The latter substances were transformed through the reaction of their magnesium chelates with

A 5C + 5C Bicycloaromatization Reaction via an Aldol Condensation Cascade: A Regioselective Synthesis of Functionalized Naphthalenes from Acyclic Precursors

A regioselective synthesis of naphthalene derivatives 51 was developed by the reaction of 1,3,5-tris(trimethylsiloxy)-1-methoxyhexa-1,3,5-triene (2) with the 1,3,5-tris-electrophiles 50 and trimethylsilyl triflate.Three carbon-carbon bonds are formed in this aldol condensation cascade, where the regiochemistry is controlled by the different reactivities at the sites of the acyclic precursors.