Cas 20376-34-5,4,6-dichloro-N-(3-chlorophenyl)-1,3,5-triazin-2-amine

20376-34-5

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Basic information

Product Name: 4,6-dichloro-N-(3-chlorophenyl)-1,3,5-triazin-2-amine
Synonyms:
CAS NO:20376-34-5
Molecular Formula: C₉H₅Cl₃N₄
Molecular Weight: 275.5218
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: 464.1°C at 760 mmHg
Flash Point: 234.5°C
Appearance: N/A
Density: 1.611g/cm³
Vapor Pressure: 8.58E-09mmHg at 25°C
Refractive Index: 1.679
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 4,6-dichloro-N-(3-chlorophenyl)-1,3,5-triazin-2-amine(CAS DataBase Reference)
NIST Chemistry Reference: 4,6-dichloro-N-(3-chlorophenyl)-1,3,5-triazin-2-amine(20376-34-5)
EPA Substance Registry System: 4,6-dichloro-N-(3-chlorophenyl)-1,3,5-triazin-2-amine(20376-34-5)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 20376-34-5(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 20376-34-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,3,7 and 6 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 20376-34:
(7*2)+(6*0)+(5*3)+(4*7)+(3*6)+(2*3)+(1*4)=85
85 % 10 = 5
So 20376-34-5 is a valid CAS Registry Number.

20376-34-5Upstream product

20376-34-5Downstream Products

20376-34-5Relevant academic research and scientific papers

Triazine compound as well as preparation method and application thereof

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Paragraph 0027; 0028; 0029; 0055; 0056; 0057, (2017/11/30)

The invention provides a triazine compound shown as a chemical formula (I) and a preparation method thereof as well as an application of the triazine compound in preparing drugs for treating central nervous system diseases. In the formula, R1 is selected

N4-Phenyl modifications of N2-(2-hydroxyl)ethyl-6-(pyrrolidin-1-yl)-1,3,5-triazine-2,4-d iamines enhance glucocerebrosidase inhibition by small molecules with potential as chemical chaperones for Gaucher disease

Huang, Wenwei,Zheng, Wei,Urban, Daniel J.,Inglese, James,Sidransky, Ellen,Austin, Christopher P.,Thomas, Craig J.

, p. 5783 - 5789 (2008/02/13)

A series of 1,3,5-triazine-2,4,6-triamines were prepared and analyzed as inhibitors of glucocerebrosidase. Synthesis, structure activity relationships and the selectivity of chosen analogues against related sugar hydrolases enzymes are described.

Triaminotriazine DNA helicase inhibitors with antibacterial activity

McKay, Geoffrey A.,Reddy, Ranga,Arhin, Francis,Belley, Adam,Lehoux, Dario,Moeck, Greg,Sarmiento, Ingrid,Parr, Thomas R.,Gros, Philippe,Pelletier, Jerry,Far, Adel Rafai

, p. 1286 - 1290 (2007/10/03)

Screening of a chemical library in a DNA helicase assay involving the Pseudomonas aeruginosa DnaB helicase provided a triaminotriazine inhibitor with good antibacterial activity but associated cytotoxicity toward mammalian cells. Synthesis of analogs provided a few inhibitors that retained antibacterial activity and demonstrated a significant reduction in cytotoxicity. The impact of serum and initial investigations toward a mode of action highlight several features of this class of compounds as antibacterials.

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