20443-03-2

Basic information

• Product Name: Dimethyl 4-oxo-1,4-dihydropyridine-2,6-dicarboxylate
• Synonyms: Dimethyl 4-oxo-1,4-dihydropyridine-2,6-dicarboxylate
• CAS NO: 20443-03-2
• Molecular Formula: C₉H₉NO₅
• Molecular Weight: 211.17146
• Mol File: 20443-03-2.mol
• Article Data: 12

Chemical Properties

• Melting Point: 169-169.5 °C(Solv: methanol (67-56-1))
• Boiling Point: 349.0±42.0 °C(Predicted)
• Appearance: /
• Density: 1.346±0.06 g/cm3(Predicted)
• PKA: 5.77±0.69(Predicted)
• CAS DataBase Reference: Dimethyl 4-oxo-1,4-dihydropyridine-2,6-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Dimethyl 4-oxo-1,4-dihydropyridine-2,6-dicarboxylate(20443-03-2)
• EPA Substance Registry System: Dimethyl 4-oxo-1,4-dihydropyridine-2,6-dicarboxylate(20443-03-2)

Safety Data

• Hazardous Substances Data: 20443-03-2(Hazardous Substances Data)

Upstream product

• 99-32-1 chelidonic acid 
• 138-60-3 chelidamic acid 
• 77-76-9 2,2-dimethoxy-propane 
• 67-56-1 methanol 
• 184870-12-0 1,4-dihydro-4-oxopyridine-2,6-dicarbonyl dichloride 

Downstream Products

• 99097-42-4 4-benzyloxypyridine-2,6-dicarboxylic dimethyl ester 
• 19872-93-6 dimethyl 4-methoxypyridine-2,6-dicarboxylate 
• 1236926-61-6 dimethyl 4-(4-fluoro-benzyloxy)-pyridine-2,6-dicarboxylate 
• 120491-88-5 4-bromo-2,6-pyridinedimethanol 
• 106967-42-4 4-bromo-2,6-bis(bromomethyl)pyridine 
• 1085412-35-6 4-(2-(tert-butoxycarbonylamino)ethoxy)-2,6-pyridinedicarboxylic acid 
• 1236183-23-5 C₂₈H₃₂N₄O₇ 
• 1236183-21-3 C₂₉H₃₄N₄O₇ 

Relevant articles and documents

Synthetic Approaches to the Bifunctional Chelators for Radio nuclides Based on Pyridine-Containing Azacrown Compounds

Synthetic ways to introduce functional groups (CO 2 Me, CO 2 H, OCH 2 CO 2 H, OCH 2 C≡CH, CH 2 OH, CH 2 Cl, CH 2 N 3) into the pyridine ring of pyridine-containing azacrown compounds are described. These groups were introduced at position-4 of the pyridine ring, while keeping the macrocyclic carboxylate groups available for metal chelation. The derivatives were obtained by macrocyclization reaction of 4-substituted, trimethyl pyridine-2,4,6-tricarboxylate or by modification of methyl ester group in pyridine fragment of macrocycles. Obtained derivatives can be applied for preparing radiotherapeutic agents by conjugation to different vector biomolecules for targeted drug delivery to cancer cells without damaging healthy tissue.

Picolinamide oligomers, preparation method and applications thereof

The invention belongs to the technical field of membrane separation, and more specifically relates to picolinamide oligomers, a preparation method and applications thereof. The picolinamide oligomerscomprise the following characteristics: 1. the oligomers

The Synthesis of Group 10 and 11 Metal Complexes of 3,6,9-Trithia-1-(2,6)-pyridinacyclodecaphane and Their Use in A3-Coupling Reactions

The reaction between 3,6,9-trithia-1(2,6)-pyridinacyclodecaphane and representative group 10 and 11 metal salts [Cu(NO3)2, NiCl2 or Ag(CF3CO2)] afforded 1:1 complexes, which in the case of CuII and AgI were characterised by single-crystal X-ray crystallography. The catalytic activity of these complexes in A3-coupling reactions between aldehydes, terminal alkynes and amines was assessed in both protic (water) and aprotic (toluene) media. These A3-reactions prove to be more efficient, proceed with lower catalyst loadings and with faster reaction rates, when conducted in a focused microwave reactor as compared to the same reactions promoted by standard, thermal, modes of activation.