204840-46-0Relevant articles and documents
Identification and sar for a selective, nonpeptidyl thrombin inhibitor
Naylor-Olsen, Adel M.,Ponticello, Gerald S.,Lewis, S. Dale,Mulichak, Anne M.,Chen, Zhonguo,Habecker, Charles N.,Phillips, Brian T.,Sanders, William M.,Tucker, Thomas J.,Shafer, Jules A.,Vacca, Joseph P.
, p. 1697 - 1702 (1998)
A novel, nonpeptidyl thrombin inhibitor, L-636,619 (1), was identified via topological similarity searching over the Merck Corporate Sample Database. X-ray crystallographic studies determined the geometry for ligand binding to the enzyme. Chemical modific
THROMBIN INHIBITORS
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, (2008/06/13)
A compound which inhibits human thrombin and which has the general structure STR1
