Bioorganic and Medicinal Chemistry Letters p. 1697 - 1702 (1998)
Update date:2022-08-05
Topics:
Naylor-Olsen, Adel M.
Ponticello, Gerald S.
Lewis, S. Dale
Mulichak, Anne M.
Chen, Zhonguo
Habecker, Charles N.
Phillips, Brian T.
Sanders, William M.
Tucker, Thomas J.
Shafer, Jules A.
Vacca, Joseph P.
A novel, nonpeptidyl thrombin inhibitor, L-636,619 (1), was identified via topological similarity searching over the Merck Corporate Sample Database. X-ray crystallographic studies determined the geometry for ligand binding to the enzyme. Chemical modific
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(1998)Doi:10.1039/C19680000976
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(1998)Doi:10.1016/S0040-4039(98)00305-0
(1998)
