204850-72-6Relevant academic research and scientific papers
Facile synthesis and PET imaging of a novel potential heart acetylcholinesterase tracer N-[11C]methyl-3-[[(dimethylamino) carbonyl]oxy]-2-(2′,2′-diphenylpropionoxymethyl)pyridinium
Wang, Ji-Quan,Miller, Michael A.,Mock, Bruce H.,Lopshire, John C.,Groh, William J.,Zipes, Douglas P.,Hutchins, Gary D.,Zheng, Qi-Huang
, p. 4510 - 4514 (2005)
A new AChE tracer N-[11C]methyl-3-[[(dimethylamino)carbonyl]oxy] -2-(2′,2′-diphenylpropionoxymethyl)pyridinium ([11C]MDDP, [11C]1) has been synthesized in 40-65% radiochemical yield. Initial PET dynamic studies of [11
Pyridophens: Binary pyridostigmine-aprophen prodrugs with differential inhibition of acetylcholinesterase, butyrylcholinesterase, and muscarinic receptors
Leader, Haim,Wolfe, Alan David,Chiang, Peter K.,Gordon, Richard K.
, p. 902 - 910 (2007/10/03)
A series of "binary prodrugs" called carbaphens, carbamylated derivatives on one or both of the aromatic rings of the muscarinic receptor antagonist aprophen [(N,N-diethylamino)ethyl 2,2-diphenylpropionate], were synthesized to develop binary prophylactic
