20498-64-0

Usage

Uses

Used in Pharmaceutical Industry:
1-(4-bromophenyl)-2-phenylethan-1-ol is used as a reagent for introducing the 4-bromophenyl group into organic molecules, which is crucial for the synthesis of pharmaceutical compounds with specific therapeutic properties.
Used in Organic Synthesis:
In the field of organic synthesis, 1-(4-bromophenyl)-2-phenylethan-1-ol serves as a versatile building block for creating more complex molecules with diverse applications, including those in the pharmaceutical, chemical, and materials science industries.
Used in Chemical Reactions:
1-(4-bromophenyl)-2-phenylethan-1-ol is utilized as a reagent in various chemical reactions, where its unique structure allows for the formation of new bonds and the creation of novel organic molecules with potential uses in different sectors.

Upstream product

• 100-39-0 benzyl bromide 
• 1122-91-4 4-bromo-benzaldehyde 
• 134988-30-0 benzyldibutyltelluronium bromide 
• 2001-29-8 1-(4-bromophenyl)-2-phenyl-ethan-1-one 
• 31593-52-9 2-benzyl-1,3-dithiane 
• 122-78-1 phenylacetaldehyde 
• 1589-82-8 phenylmagnesium bromide 
• 2039-82-9 1-bromo-4-ethenyl-benzene 
• 100-63-0 phenylhydrazine 

Downstream Products

• 60313-43-1 1-bromo-4-(1-bromo-2-phenylethyl)benzene 
• 60313-60-2 2-(1-(4-bromophenyl)-2-phenylethyl)malonic acid 
• 60313-13-5 3-(4-bromophenyl)-3,4-dihydro-2H-naphthalen-1-one 

Relevant academic research and scientific papers

Anticoagulant raticide hapten and artificial antigen, and preparation methods and applications thereof

The invention relates to an anticoagulant raticide hapten and an artificial antigen, and preparation methods and applications thereof. The structure of the anticoagulant rodent hapten is represented by formula (I); and the anticoagulant rodent artificial

Enantioselective 1,2-Anionotropic Rearrangement of Acylsilane through a Bisguanidinium Silicate Ion Pair

Highly enantioselective bisguanidinium-catalyzed tandem rearrangements of acylsilanes are reported. The acylsilanes were activated via an addition of fluoride on the silicon to form a penta-coordinate anionic silicate intermediate. The silicate then underwent alkyl or aryl group migration from the silicon atom to the neighboring carbonyl carbon atom (1,2-anionotropic rearrangement), followed by [1,2]-Brook rearrangement to provide the secondary alcohols in high yields with excellent enantioselectivities (up to 95% ee). The isolation of an α-silylcarbinol intermediate as well as DFT calculations revealed that the 1,2-anionotropic rearrangement occurred via a bisguanidinium silicate ion pair, which is the stereodetermining step. The chiral center formed is then retained without inversion through the subsequent [1,2]-Brook rearrangement. Crotyl acylsilanes were smoothly transformed into homoallylic linear crotyl alcohols with retention of E/Z geometry, and no branched alcohols were detected. This clearly suggested that the 1,2-anionotropic rearrangement occurred through a three-membered instead of a five-membered transition state.

Pd-Catalyzed Conjunctive Cross-Coupling between Grignard-Derived Boron “Ate” Complexes and C(sp2) Halides or Triflates: NaOTf as a Grignard Activator and Halide Scavenger

Catalytic enantioselective conjunctive cross-couplings that employ Grignard reagents are shown to furnish an array of nonracemic chiral organoboronic esters in an efficient and highly selective fashion. The utility of sodium triflate in facilitating this reaction is two-fold: it enables “ate” complex formation and overcomes catalytic inhibition by halide ions.

Catalyst-controlled highly selective coupling and oxygenation of olefins: A direct approach to alcohols, ketones, and diketones

Oxygen? That's radical! A method for the direct synthesis of substituted alcohols, ketones, and diketones through a catalyst-controlled highly chemoselective coupling and oxygenation of olefins has been developed. The method is simple and practical, can be switched by the selection of different catalysts, and employs molecular oxygen as both an oxidant and a reagent. Copyright

A new, simple, efficient electrosynthesis of functionalized benzylic zinc species and their reactivity toward aromatic aldehydes

Various stable substituted benzylic zincs are formed in acetonitrile upon reaction of the bromide derivatives, in good yields, using a catalytic electrogenerated zinc species associated with massive zinc. In the presence of chlorotrimethylsilone, these or

Reactions of Carbonyl Compounds with Benzyldibutyltelluronium Bromide Mediated by Different Strong Bases

Reactions of carbonyl compounds with benzyldibutyltelluronium bromide mediated by alkyllithium or Grignard reagent give homobenzylic aclohols, while those mediated by potassium t-butoxide give olefins.