205035-66-1Relevant academic research and scientific papers
Synthesis and Cytokinin Activity of New Zeatin Derivatives
Haidoune, M'Barek,Raynaud, Isabelle,O'Connor, Norval,Richomme, Pascal,Mornet, Rene,Laloue, Michel
, p. 1577 - 1582 (1998)
The analogue of zeatin bearing a vinylic fluorine atom and its geometrical isomer were synthesized. The fluorine atom exerts a favorable influence on cytokinin activity in the fluoro analogue of ciszeatin, but not in the fluoro analogue of zeatin itself. Another series of zeatin derivatives in which the methyl group was replaced by alkyl (ethyl, propyl, and isopropyl), phenyl, and benzyl groups were also obtained. The ethyl analogue was found to be more active than zeatin, while the others were inactive or slightly active.
Enantioselective CuH-catalyzed anti-markovnikov hydroamination of 1,1-disubstituted alkenes
Zhu, Shaolin,Buchwald, Stephen L.
supporting information, p. 15913 - 15916 (2015/02/19)
Enantioselective synthesis of β-chiral amines has been achieved via copper-catalyzed hydroamination of 1,1-disubstituted alkenes with hydroxylamine esters in the presence of a hydrosilane. This mild process affords a range of structurally diverse β-chiral amines, including β-deuterated amines, in excellent yields with high enantioselectivities. Furthermore, catalyst loading as low as 0.4 mol% could be employed to deliver product in undiminished yield and selectivity, demonstrating the practicality of this method for large-scale synthesis.
