658080-23-0Relevant academic research and scientific papers
Design and application of hybrid phosphorus ligands for enantioselective Rh-Catalyzed anti-markovnikov hydroformylation of unfunctionalized 1,1-disubstituted Alkenes
You, Cai,Li, Shuailong,Li, Xiuxiu,Lan, Jialing,Yang, Yuhong,Chung, Lung Wa,Lv, Hui,Zhang, Xumu
, p. 4977 - 4981 (2018)
A series of novel hybrid phosphorus ligands were designed and applied to the Rh-catalyzed enantioselective anti-Markovnikov hydroformylation of unfunctionalized 1,1-disubstituted alkenes. By employing the new catalyst, linear aldehydes with β-chirality can be prepared with high yields and enantioselectivities under mild conditions. Furthermore, catalyst loading as low as 0.05 mol % furnished the desired product in good yield and undiminished selectivity, demonstrating the efficiency of this transformation in large-scale synthesis.
Enantioselective Synthesis of the Spirotetracyclic Carbon Core of Mangicols by Using a Stereoselective Transannnnular Diels-Alder Strategy
Araki, Keisuke,Saito, Keiji,Arimoto, Hirokazu,Uemura, Daisuke
, p. 81 - 84 (2007/10/03)
"TADA!" is not the trumpet fanfare but the transannular Diels-Alder reaction concluding the synthesis of the tetracyclic core of the mangicols, a family of marine sesterterpenes. Further highlights in the synthesis include a novel chlorination and an intr
