205756-24-7

Basic information

• Product Name: 4-CHLORO-2-TRIFLUOROACETYL-6-(TERT-BUTYLDIMETHYLSILYLOXY)ANILINE
• Synonyms: 4-CHLORO-2-TRIFLUOROACETYL-6-(TERT-BUTYLDIMETHYLSILYLOXY)ANILINE;1-[2-AMino-5-chloro-3-[[(1,1-diMethylethyl)diMethylsilyl]oxy]phenyl]-2,2,2-trifluoro-ethanone
• CAS NO: 205756-24-7
• Molecular Formula: C₁₄H₁₉ClF₃NO₂Si
• Molecular Weight: 353.8398696
• Product Categories: Chemical Amines;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 205756-24-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Methanol
• CAS DataBase Reference: 4-CHLORO-2-TRIFLUOROACETYL-6-(TERT-BUTYLDIMETHYLSILYLOXY)ANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-2-TRIFLUOROACETYL-6-(TERT-BUTYLDIMETHYLSILYLOXY)ANILINE(205756-24-7)
• EPA Substance Registry System: 4-CHLORO-2-TRIFLUOROACETYL-6-(TERT-BUTYLDIMETHYLSILYLOXY)ANILINE(205756-24-7)

Safety Data

• Hazardous Substances Data: 205756-24-7(Hazardous Substances Data)

Usage

Chemical Properties

Orange Solid

Uses

4-Chloro-2-trifluoroacetyl-6-(tert-butyldimethylsilyloxy)aniline (cas# 205756-24-7_x000D__x000D_) is a compound useful in organic synthesis.

Upstream product

• 69739-34-0 t-butyldimethylsiyl triflate 
• 205756-23-6 2'-amino-5'-chloro-3'-hydroxy-2,2,2-trifluoroacetophenone 
• 93-50-5 4-chloro-o-anisidine 
• 288-32-4 1H-imidazole 
• 205756-22-5 2'-amino-5'-chloro-3'-methoxy-2,2,2-trifluoroacetophenone 
• 113137-29-4 N-(4-chloro-2-methoxyphenyl)-2,2-dimethylpropanamide 
• 6627-53-8 1-chloro-3-methoxy-4-nitrobenzene 

Downstream Products

• 205756-25-8 2-(2-Amino-5-chloro-3-(t-butyldimethylsilyloxy)-phenyl)-4-cyclopropyl-1,1,1-trifluoro-3-butyn-2-ol 
• 1027042-31-4 8-(tert-butyl-dimethyl-silanyloxy)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one 
• 205754-32-1 6-chloro-4-cyclopropylethynyl-8-hydroxy-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one 
• 205754-33-2 8-Hydroxyefavirenz 

Relevant articles and documents

4,4-DISUBSTITUTED-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONES USEFUL AS HIV REVERSE TRANSCRIPTASE INHIBITORS AND INTERMEDIATES AND PROCESSES FOR MAKING THE SAME

The present invention relates to benzoxazinones of formula I, or stereoisomeric forms or mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, methods of using same for treating viral infection or as an assay standard or reagent, and intermediates and processes for making the same.

4,4-disubstitued-1,4-dihydro-2H-3,1-benzoxazin-2-ones useful as HIV reverse transcriptase inhibitors and intermediates and processes for making the same

The present invention relates to benzoxazinones of formula I: STR1 or stereoisomeric forms or mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, methods of using the same for treating viral infection or as an assay standard or reagent, and intermediates and processes for making the same.