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1027042-31-4

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  • 8-[tert-butyl(dimethyl)silyl]oxy-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one

    Cas No: 1027042-31-4

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1027042-31-4 Usage

Chemical Properties

Off-White Solid

Uses

Different sources of media describe the Uses of 1027042-31-4 differently. You can refer to the following data:
1. Efavirenz (E425000) intermediate.
2. Efavirenz intermediate.

Check Digit Verification of cas no

The CAS Registry Mumber 1027042-31-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,7,0,4 and 2 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1027042-31:
(9*1)+(8*0)+(7*2)+(6*7)+(5*0)+(4*4)+(3*2)+(2*3)+(1*1)=94
94 % 10 = 4
So 1027042-31-4 is a valid CAS Registry Number.

1027042-31-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 8-[tert-butyl(dimethyl)silyl]oxy-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:1027042-31-4 SDS

1027042-31-4Relevant articles and documents

Synthesis and biological activities of potential metabolites of the non-nucleoside reverse transcriptase inhibitor efavirenz

Markwalder, Jay A.,Christ, David D.,Mutlib, Abdul,Cordova, Beverly C.,Klabe, Ronald M.,Seitz, Steven P.

, p. 619 - 622 (2007/10/03)

Studies on the biotransformation of the clinically important non-nucleoside reverse transcriptase inhibitor efavirenz have shown that oxidation and secondary conjugation are important components of the processing of this molecule in vivo. We have synthesized metabolites of efavirenz to confirm their structure and to evaluate their activity as antivirals.

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